SCHEMBL515813

SCHEMBL515813

CCOC(=O)C(C)=CC(CC)NC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.40
MAPT P10636 3/20 0.37
CYP2D6 P10635 3/20 0.36
CYP2C19 P33261 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
S1PR4 O95977 1/20 0.36
S1PR1 P21453 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.35
GAA P10253 3/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6672423 0.85 GLO1 (0.37) GLO1MAPTCYP2D6CYP2C19NPSR1
SCHEMBL6672418 0.85 GLO1 (0.37) GLO1MAPTCYP2D6CYP2C19NPSR1
Hydrochloric Acid SCHEMBL6673606 0.83 GLO1 (0.36) GLO1MAPTCYP2D6CYP2C19NPSR1
Hydrochloric Acid SCHEMBL6673610 0.83 GLO1 (0.36) GLO1MAPTCYP2D6CYP2C19NPSR1
SCHEMBL58098 0.79 GLO1 (0.40) GLO1MAPTCYP2D6CYP2C19NPSR1
SCHEMBL88552 0.79 GLO1 (0.40) GLO1MAPTCYP2D6CYP2C19NPSR1
SCHEMBL7096152 0.77 AKR1C3 (0.32)
SCHEMBL2053892 0.76 KDM4E (0.34) KDM4E
SCHEMBL5076118 0.75 GLO1 (0.47) GLO1MAPTCYP2D6CYP2C19NPSR1
SCHEMBL5076122 0.75 GLO1 (0.47) GLO1MAPTCYP2D6CYP2C19NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150094448-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES MEDIPACS, INC. 2015-04-02 US claimed
EP-2847249-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES Medipacs, Inc. (US) 2015-03-18 EP claimed
WO-2013138524-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES MEDIPACS, INC. (US) 2013-09-19 WO claimed
US-10000605-B2 Smart polymer materials with excess reactive molecules MEDIPACS, INC. (US) 2018-06-19 US disclosed
US-20170069824-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS MEDIPACS INC (US) 2017-03-09 US disclosed
US-9500186-B2 High surface area polymer actuator with gas mitigating components MEDIPACS, INC. (US) 2016-11-22 US disclosed
US-20160206817-A1 LOW PROFILE ACTUATOR AND IMPROVED METHOD OF CAREGIVER CONTROLLED ADMINISTRATION OF THERAPEUTICS MEDIPACS INC (US) 2016-07-21 US disclosed
US-9238102-B2 Low profile actuator and improved method of caregiver controlled administration of therapeutics MEDIPACS, INC. (US) 2016-01-19 US disclosed
US-20150094448-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES MEDIPACS, INC. 2015-04-02 US disclosed
US-20140221913-A1 LOW PROFILE INFUSION PUMP WITH ANTI DRUG DIVERSION AND ACTIVE FEEDBACK MECHANISMS MEDIPACS, INC. (US) 2014-08-07 US disclosed
EP-2760497-A1 LOW PROFILE INFUSION PUMP WITH ANTI DRUG DIVERSION AND ACTIVE FEEDBACK MECHANISMS Medipacs, Inc. (US) 2014-08-06 EP disclosed
WO-2013049070-A1 LOW PROFILE INFUSION PUMP WITH ANTI DRUG DIVERSION AND ACTIVE FEEDBACK MECHANISMS MEDIPACS, INC. (US) 2013-04-04 WO disclosed
EP-2531549-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS Medipacs, Inc. (US) 2012-12-12 EP disclosed
US-20120191060-A1 LOW PROFILE ACTUATOR AND IMPROVED METHOD OF CAREGIVER CONTROLLED ADMINISTRATION OF THERAPEUTICS MEDIPACS, INC. 2012-07-26 US disclosed
US-20120029430-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS MEDIPACS, INC. 2012-02-02 US disclosed
WO-2011094747-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS MEDIPACS, INC. (US) 2011-08-04 WO disclosed
WO-2011032011-A1 LOW PROFILE ACTUATOR AND IMPROVED METHOD OF CAREGIVER CONTROLLED ADMINISTRATION OF THERAPEUTICS MEDIPACS, INC. (US) 2011-03-17 WO disclosed