Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929575 | 1.00 | KMT2A (0.60) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL27728696 | 0.79 | KMT2A (0.50) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL15291349 | 0.78 | KMT2A (0.62) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL11151822 | 0.78 | KMT2A (0.58) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL15272598 | 0.78 | KMT2A (0.58) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL15272327 | 0.78 | KMT2A (0.58) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL2480787 | 0.78 | KMT2A (0.61) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL10147174 | 0.77 | KMT2A (0.48) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL2454068 | 0.77 | KMT2A (0.60) | KMT2APOLBPTPN1L3MBTL1PKM | |
| SCHEMBL2454069 | 0.77 | KMT2A (0.60) | KMT2APOLBPTPN1L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |