SCHEMBL2480787

SCHEMBL2480787

CC(C(=O)O)c1ccco1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
POLB P06746 3/20 0.61
PTPN1 P18031 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
PKM P14618 1/20 0.61
PTPN7 P35236 1/20 0.61
BLM P54132 1/20 0.61
ESR2 Q92731 1/20 0.61
ALOX5 P09917 1/20 0.50
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
AGTR1 P30556 1/20 0.46
CYP2C19 P33261 2/20 0.44
PTGS2 P35354 2/20 0.44
PTGS1 P23219 1/20 0.44
MIF P14174 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9402317 0.98 KMT2A (0.59) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL11538261 0.87 KMT2A (0.52) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL27536602 0.84 KMT2A (0.52) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL3577958 0.81 ALOX5 (0.58) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL9402314 0.81 ALOX5 (0.49) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL15291349 0.79 KMT2A (0.62) KMT2APOLBPTPN1L3MBTL1PKM
Hydrochloric Acid SCHEMBL5352590 0.79 ALOX5 (0.56) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL5511586 0.79 KMT2A (0.57) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL31612145 0.78 HTT (0.43) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL5158147 0.78 KMT2A (0.60) KMT2APOLBPTPN1L3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3509647-B1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2020-10-21 EP claimed
CN-105693772-B A kind of compound and its application in DNA end group modifications 中国石油大学(华东) 2017-03-15 CN claimed
CN-105693772-A Compound and application thereof to DNA end group modification 中国石油大学(华东) 2016-06-22 CN claimed
EP-1945224-B1 REDUCTION OF SIDE EFFECTS FROM AROMATASE INHIBITORS USED FOR TREATING BREAST CANCER CHAVAH PTY LTD (AU) 2012-05-02 EP claimed
EP-1359920-B1 USES OF ORAL FORMULATIONS FOR THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION BARR LAB INC (US) 2007-08-22 EP claimed
US-20050042268-A1 Pharmaceutical composition and method for transdermal drug delivery PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) 2005-02-24 US claimed
US-6844302-B1 Encapsulated flavor and fragrance INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-01-18 US claimed
JP-3034046-B2 2000-04-17 JP claimed
EP-0691953-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-01-17 EP claimed
WO-1994022820-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-10-13 WO claimed
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 US disclosed
US-12528801-B2 Substituted azacyles as TRPM8 modulators GIVAUDAN SA (CH) 2026-01-20 US disclosed
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US disclosed
US-20250186600-A1 EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS COMERA LIFE SCIENCES, INC. 2025-06-12 US disclosed
CN-114555594-B Substituted azacycles as TRMP modulators 奇华顿股份有限公司 2025-03-18 CN disclosed
EP-0076721-B1 PROCESS FOR THE CARBONYLATION OF SECONDARY BENZYL HALIDES Montedison S.p.A. (IT) 1985-02-06 EP disclosed
EP-0076721-A1 Process for the carbonylation of secondary benzyl halides Montedison S.p.A. (IT) 1983-04-13 EP disclosed
US-4107178-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1978-08-15 US disclosed
US-4086420-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-04-25 US disclosed
US-4051151-A Thiophene derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS TRPM8, TRPM7, TRPM5 KMT2A 2019/4885POLB 4267/4885PTPN1 2038/4885
US-12528801-B2 Substituted azacyles as TRPM8 modulators TRPM8, TRPM7, TRPM4 KMT2A 2021/4885POLB 4565/4885PTPN1 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.