Sugi Predict

Sugi Predict / Compounds / SCHEMBL10147174

SCHEMBL10147174

SCHEMBL10147174

CC(C)C(O)c1ccco1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.48
▸ POLB P06746 4/20 0.48
▸ PKM P14618 1/20 0.48
▸ PTPN1 P18031 1/20 0.48
▸ PTPN7 P35236 1/20 0.48
▸ BLM P54132 1/20 0.48
▸ ESR2 Q92731 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ ALDH1A1 P00352 5/20 0.46
▸ MEN1 O00255 4/20 0.46
▸ MAPT P10636 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ ALOX5 P09917 1/20 0.44
▸ AGTR1 P30556 1/20 0.44
▸ HSD17B10 Q99714 3/20 0.41
▸ HPGD P15428 3/20 0.39
▸ TP53 P04637 1/20 0.39
▸ ATM Q13315 1/20 0.36
▸ MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL28482440 0.94 KMT2A (0.44) KMT2APOLBPKMPTPN1PTPN7
SCHEMBL27728696 0.88 KMT2A (0.50) KMT2APOLBPKMPTPN1PTPN7
SCHEMBL15272327 0.87 KMT2A (0.58) KMT2APOLBPKMPTPN1PTPN7
SCHEMBL11151822 0.87 KMT2A (0.58) KMT2APOLBPKMPTPN1PTPN7
SCHEMBL15272598 0.87 KMT2A (0.58) KMT2APOLBPKMPTPN1PTPN7
SCHEMBL21029965 0.86 KMT2A (0.45) KMT2APOLBPKMPTPN1PTPN7
SCHEMBL14944873 0.82 KDM4E (0.48) KMT2APOLBPKMPTPN1PTPN7
SCHEMBL1133548 0.80 — —
SCHEMBL4088167 0.80 — —
SCHEMBL11150700 0.80 KMT2A (0.52) KMT2APOLBPKMPTPN1PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11116212-B2 Carbonyl containing compounds for controlling and repelling Cimicidae populations SEMIOSBIO TECHNOLOGIES INC. (CA) 2021-09-14 — — US disclosed
US-11116212-B2 Carbonyl containing compounds for controlling and repelling Cimicidae populations SEMIOSBIO TECHNOLOGIES INC. (CA) 2021-09-14 — — US disclosed
CN-109180624-A A kind of preparation method of novel 6- hydroxyl -2H- pyrans -3- ketone 大连理工大学 2019-01-11 — — CN disclosed
US-9981919-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICAL N.V. (BE) 2018-05-29 — — US disclosed
US-9981919-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICAL N.V. (BE) 2018-05-29 — — US disclosed
US-20170320835-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2017-11-09 — — US disclosed
US-20170320835-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2017-11-09 — — US disclosed
US-20170121292-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2017-05-04 — — US disclosed
US-9580392-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2017-02-28 — — US disclosed
US-9580392-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2017-02-28 — — US disclosed
US-8828982-B2 Pyrimidine derivatives for the prevention of HIV infection JANSSEN PHARMACEUTICA N.V. (BE) 2014-09-09 — — US disclosed
WO-2012129702-A1 CARBONYL CONTAINING COMPOUNDS FOR CONTROLLING AND REPELLING CIMICIDAE POPULATIONS SEMIOSBIO TECHNOLOGIES INC. (CA) 2012-10-04 — — WO disclosed
US-20120076835-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES GUILLEMONT JEROME EMILE GEORGES (FR) 2012-03-29 — — US disclosed
US-8080551-B2 HIV inhibiting pyrimidines derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2011-12-20 — — US disclosed
US-8080551-B2 HIV inhibiting pyrimidines derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2011-12-20 — — US disclosed
US-20100034810-A1 PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION JANSSEN-CILAG (FR) 2010-02-11 — — US disclosed
US-7179878-B2 Poly(arylene ether) polymer with low temperature or UV crosslinking grafts and dielectric comprising the same Delsper LP 2007-02-20 — — US disclosed
US-7179878-B2 Poly(arylene ether) polymer with low temperature or UV crosslinking grafts and dielectric comprising the same Delsper LP 2007-02-20 — — US disclosed
US-20070021449-A1 Pyrimidine derivatives for the prevention of hiv infection HEERES JAN 2007-01-25 — — US disclosed
US-4496767-A REARRANGEMENT, ESTERIFICATION AND REDUCTION OF A FURAN-CARBINOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170121292-A1 HIV REPLICATION INHIBITING PYRIMIDINES RRM2B, CCNO, RRM2 KMT2A 2086/4885POLB 50/4885PKM 2205/4885
US-20070021449-A1 Pyrimidine derivatives for the prevention of hiv infection ADORA2B, CYP1B1, DPYD KMT2A 2620/4885POLB 293/4885PKM 2592/4885
US-20120076835-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES TYMS, PNP, DUT KMT2A 2281/4885POLB 18/4885PKM 2065/4885
US-20100034810-A1 PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION NOX3, CBR3, CBR1 KMT2A 3053/4885POLB 1486/4885PKM 2719/4885
US-20170320835-A1 HIV REPLICATION INHIBITING PYRIMIDINES RRM2B, CCNO, RRM2 KMT2A 2086/4885POLB 50/4885PKM 2205/4885
US-11116212-B2 Carbonyl containing compounds for controlling and repelling Cimicidae populations DDT, AOC1, EGLN1 KMT2A 798/4885POLB 3757/4885PKM 2156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.