SCHEMBL5158249

SCHEMBL5158249

O=CCCCC(=O)C(=O)C=O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.43
TSHR P16473 2/20 0.36
MAPT P10636 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
FAAH O00519 2/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5032513 0.84 HIF1A (0.33) HIF1A
SCHEMBL1331668 0.84 HIF1A (0.53) HIF1ATSHRMAPTCES2CES1
SCHEMBL30213710 0.79 HIF1A (0.47) HIF1ATSHRMAPTCES2CES1
SCHEMBL29439095 0.78 TRPA1 (0.38) HIF1ATSHRMAPT
SCHEMBL1296671 0.77 OR51E2 (0.50) HIF1ATSHRMAPTCES2CES1
SCHEMBL30439607 0.75 FAAH (0.48) HIF1ATSHRMAPTCES2CES1
SCHEMBL28719019 0.75 CES1 (0.62) CES2CES1FAAH
SCHEMBL711379 0.74
SCHEMBL158722 0.74
SCHEMBL28774839 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043627-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2024-02-08 US claimed
WO-2023137224-A2 BIODEGRADABLE MICROCAPSULES WITH IMPROVED STORAGE STABILITY, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2023-07-20 WO claimed
US-11639485-B2 Direct alkoxylation of bio-oil BATTELLE MEMORIAL INSTITUTE (US) 2023-05-02 US claimed
US-20230023873-A1 COLLAGEN-ARGINATE WOUND DRESSING MATERIAL AND METHOD FOR PRODUCING SAME PLMICROMED CO., LTD. (KR) 2023-01-26 US claimed
WO-2021132741-A1 EMBOLIZATION PARTICLES, AND METHOD FOR PREPARING SAME 주식회사 피엘마이크로메드 2021-07-01 WO claimed
EP-3842077-A1 EMBOLIZATION PARTICLES AND METHOD FOR PREPARING THE SAME Plmicromed Co., Ltd. (KR) 2021-06-30 EP claimed
US-20210188946-A1 EMBOLIZATION PARTICLES AND METHODS FOR PREPARING THE SAME PLMICROMED CO., LTD. (KR) 2021-06-24 US claimed
US-20210071106-A1 DIRECT ALKOXYLATION OF BIO-OIL BATTELLE MEMORIAL INSTITUTE 2021-03-11 US claimed
US-10883067-B2 Direct alkoxylation of bio-oil BATTELLE MEMORIAL INSTITUTE (US) 2021-01-05 US claimed
US-20200140624-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2020-05-07 US claimed
US-20180289543-A1 PUNCTAL PLUG AND BIOADHESIVES OCULAR THERAPEUTIX, INC. 2018-10-11 US claimed
US-20170355927-A1 DIRECT ALKOXYLATION OF BIO-OIL BATTELLE MEMORIAL INSTITUTE 2017-12-14 US claimed
WO-2017062770-A1 PUNCTAL PLUG AND BIOADHESIVES SILVERBERG NOAH (US) 2017-04-13 WO claimed
US-20240148553-A1 PUNCTAL PLUG AND BIOADHESIVES OCULAR THERAPEUTIX, INC. 2024-05-09 US disclosed
US-20240043627-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2024-02-08 US disclosed
US-11827752-B2 Lignin hybrid polymers obtained from the reaction of lignin and compatible polymer precursors, and starting compositions for forming lignin hybrid polymers Organic Chemical, LLC (US) 2023-11-28 US disclosed
EP-0976550-A1 A method for making positive working printing plates from a latex AGFA-GEVAERT N.V. (BE) 2000-02-02 EP disclosed
US-RE33997-E A mixture of collagen and a polymer for shaping to form contact lenses ALLERGAN, INC. (US) 1992-07-14 US disclosed
EP-0070897-B1 CONTACT LENSES MADE FROM MODIFIED SYNTHETIC HYDROGELS NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1986-11-26 EP disclosed
US-4452925-A Biologically stabilized compositions comprising collagen as the minor component with ethylenically unsaturated compounds used as contact lenses NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1984-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188946-A1 EMBOLIZATION PARTICLES AND METHODS FOR PREPARING THE SAME PLAU, PLAT, PCSK9 HIF1A 387/4885TSHR 1617/4885MAPT 4777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.