Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160081 | 0.82 | PIK3CD (0.42) | PIK3CDPTGS2ACACBF2R | |
| SCHEMBL5163527 | 0.76 | PIK3CD (0.38) | PIK3CDPTGS2ACACBF2R | |
| SCHEMBL24663488 | 0.72 | PIK3CD (0.40) | PIK3CDPTGS2ACACBF2R | |
| SCHEMBL5163592 | 0.69 | GSK3B (0.56) | PTGS2 | |
| SCHEMBL24567580 | 0.69 | ACACB (0.48) | PIK3CDPTGS2ACACBF2R | |
| Hydrochloric Acid SCHEMBL28286442 | 0.69 | — | — | |
| SCHEMBL27788447 | 0.69 | — | — | |
| SCHEMBL27755491 | 0.69 | — | — | |
| Formaldehyde SCHEMBL27833978 | 0.67 | PIK3CD (0.37) | PIK3CDPTGS2ACACBF2R | |
| SCHEMBL5177516 | 0.67 | TRPA1 (0.47) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |