Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162386 | 0.77 | GPR84 (0.33) | PIK3CDPTGS2 | |
| SCHEMBL2632662 | 0.76 | — | — | |
| SCHEMBL24663488 | 0.69 | PIK3CD (0.40) | PIK3CDACACBPTGS2F2R | |
| SCHEMBL5159964 | 0.69 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL3494048 | 0.69 | GSK3B (0.56) | — | |
| SCHEMBL27788447 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL28286442 | 0.69 | — | — | |
| SCHEMBL27755491 | 0.69 | — | — | |
| SCHEMBL8865580 | 0.68 | PIK3CD (0.40) | PIK3CDACACBPTGS2F2RRIPK1 | |
| SCHEMBL4411674 | 0.68 | P2RX7 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |