Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159291 | 1.00 | DPP4 (0.47) | DPP4PDE4BTACR3RORCGPR119 | |
| SCHEMBL31174316 | 0.91 | DPP4 (0.47) | DPP4PDE4BTACR3RORCGPR119 | |
| SCHEMBL31174300 | 0.91 | DPP4 (0.47) | DPP4PDE4BTACR3RORCGPR119 | |
| SCHEMBL19270998 | 0.89 | PDE4B (0.50) | DPP4PDE4BTACR3RORCTACR1 | |
| SCHEMBL27688526 | 0.87 | RORC (0.49) | PDE4BTACR3RORCGPR119TACR1 | |
| SCHEMBL4483553 | 0.87 | RORC (0.49) | PDE4BTACR3RORCGPR119TACR1 | |
| SCHEMBL4944424 | 0.87 | RORC (0.49) | PDE4BTACR3RORCGPR119TACR1 | |
| SCHEMBL4483563 | 0.87 | RORC (0.49) | PDE4BTACR3RORCGPR119TACR1 | |
| SCHEMBL4483556 | 0.87 | RORC (0.49) | PDE4BTACR3RORCGPR119TACR1 | |
| SCHEMBL3003926 | 0.85 | PDE4B (0.53) | DPP4PDE4BTACR3RORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748984-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | Pfizer Products Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005110987-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050256164-A1 | NK1 and NK3 antagonists | PFIZER INC | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256164-A1 | NK1 and NK3 antagonists | TAC3, TACR1, TACR2 | DPP4 505/4885PDE4B 1677/4885TACR3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.