Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653632 | 0.80 | PDE4B (0.38) | BRD4ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL10192897 | 0.79 | BRD4 (0.51) | MAOBBRD4FFAR1MAOATDP1 | |
| SCHEMBL1652644 | 0.73 | PTGS1 (0.33) | BRD4ALDH1A1HPGD | |
| SCHEMBL987005 | 0.73 | KDM4E (0.35) | ALDH1A1HPGD | |
| SCHEMBL31562547 | 0.73 | MAOB (0.49) | MAOBBRD4MAOASMN1; SMN2SRD5A1 | |
| SCHEMBL10187585 | 0.72 | ACHE (0.40) | MAOBFFAR1GRM5NPC1RAB9A | |
| SCHEMBL15287372 | 0.71 | MAOB (0.47) | MAOBBRD4FFAR1MAOAGRM5 | |
| SCHEMBL15287126 | 0.71 | MAOB (0.47) | MAOBBRD4FFAR1MAOAGRM5 | |
| SCHEMBL10903897 | 0.70 | L3MBTL1 (0.55) | MAOBMAOAGRM5NPC1RAB9A | |
| SCHEMBL515204 | 0.70 | NPC1 (0.56) | MAOBMAOAGRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393769-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2014-12-10 | — | — | EP | disclosed |
| US-8680339-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-8680339-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-8680339-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-20120028800-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120028800-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120028800-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| EP-2393769-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089210-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010089210-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028800-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | MAOB 2064/4885BRD4 2341/4885FFAR1 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.