Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245408 | 0.86 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5159305 | 0.85 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL3114462 | 0.84 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4319146 | 0.83 | LTA4H (0.54) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4319155 | 0.83 | LTA4H (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4965387 | 0.81 | SLC6A3 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6625146 | 0.80 | SLC6A3 (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3855799 | 0.79 | GRM2 (0.52) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6766361 | 0.78 | KMT2A (0.49) | SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL5729711 | 0.78 | SLC6A3 (0.43) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777214-A2 | Novel aryloxy-alkyl-dialkylamines | Wyeth (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1025077-B1 | NOVEL ARYLOXY-ALKYL-DIALKYLAMINES | WYETH CORP (US) | 2007-02-28 | — | — | EP | disclosed |
| US-6268504-B1 | USED IN THE PRODUCTION OF PHARMACEUTICAL PRODUCTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6242605-B1 | Aryloxy-alkyl-dialkylamines | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |
| EP-1025077-A1 | NOVEL ARYLOXY-ALKYL-DIALKYLAMINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-09 | — | — | EP | disclosed |
| US-6005102-A | NOVEL INTERMEDIATES WHICH MAY BE USED IN THE PRODUCTION OF PHARMACEUTICAL COMPOUNDS FOR ANTI-ESTROGENIC AND MATRIX METALLOPROTEINASES-INHIBITING UTILITIES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-21 | — | — | US | disclosed |
| WO-1999019293-A1 | NOVEL ARYLOXY-ALKYL-DIALKYLAMINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-04-22 | — | — | WO | disclosed |