SCHEMBL5159135

SCHEMBL5159135

O=C(O)C(I)c1nc2ccccc2s1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
HIF1A Q16665 1/20 0.60
HSD17B10 Q99714 1/20 0.60
ALOX5 P09917 1/20 0.51
LOXL2 Q9Y4K0 1/20 0.47
RAB9A P51151 6/20 0.47
APEX1 P27695 1/20 0.46
NPC1 O15118 5/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
ALDH1A1 P00352 2/20 0.46
CSNK1D P48730 1/20 0.46
PKM P14618 2/20 0.45
NFKB1 P19838 2/20 0.45
NFKB2 Q00653 2/20 0.45
RELA Q04206 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5536307 0.81 HPGD (0.66) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL3963337 0.80 HPGD (0.60) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL11191161 0.80 HPGD (0.60) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL11697365 0.80 HPGD (0.60) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL5687666 0.80 HPGD (0.60) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL9306307 0.79 HPGD (0.58) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL9306298 0.79 HPGD (0.58) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL3787121 0.76 HPGD (0.56) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL1371913 0.76 HPGD (0.56) HPGDCYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL15149247 0.76 LOXL2 (0.63) HPGDCYP1A2CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1361477-B1 Process for chemically sensitizing a green-sensitive silver halide photographic emulsion and photographic material containing said emulsion FERRANIA TECHNOLOGIES SPA (IT) 2007-01-17 EP disclosed
EP-1361477-A1 Process for chemically sensitizing a green-sensitive silver halide photographic emulsion and photographic material containing said emulsion FERRANIA S.p.A. (IT) 2003-11-12 EP disclosed
US-6534255-B1 Tabular silver halide grains are chemically sensitized by at least one gold sensitizer and at least one thiosulfonate sensitizer in the presence of a palladium compound added during chemical sensitization EASTMAN KODAK COMPANY 2003-03-18 US disclosed
EP-0559061-B1 Method of processing a silver halide radiographic element EASTMAN KODAK CO (US) 2002-05-02 EP disclosed
EP-0560118-B1 Light-sensitive silver halide photographic element EASTMAN KODAK CO (US) 2001-08-29 EP disclosed
EP-0693707-B1 Light-sensitive silver halide photographic element EASTMAN KODAK CO (US) 2001-06-20 EP disclosed
US-6063556-A HAVING ANTISTATIC LAYER COMPRISES A COLLOIDAL VANADIUM OXIDE AND A SULFOPOLYESTER MINNESOTA MINING AND MANUFACTURING CO. (US) 2000-05-16 US disclosed
EP-0709727-B1 Silver halide photographic material comprising pyridinium carbamoyl hardeners TULALIP CONSULTORIA COMERCIAL (PT) 2000-03-22 EP disclosed
EP-0647879-B1 Silver halide photographic material having improved antistatic properties IMATION CORP (US) 1999-12-29 EP disclosed
EP-0661592-B1 Radiographic assembly for chest examination IMATION CORP (US) 1999-09-22 EP disclosed
US-5354648-A A medical equipment to reduce the x-ray dosage received by patient using a intensifying screens with coated silver halide emulsion; protective devices MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-11 US disclosed
EP-0618490-A1 Silver halide photographic material having improved antistatic properties MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-05 EP disclosed
US-5318881-A Developer and fixing solutions free of boric acid and gelatin hardeners, tubular grains, low swelling MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-07 US disclosed
EP-0591747-A1 Multicontrast radiographic film-screen assembly MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-04-13 EP disclosed
US-5302505-A Tabular silver halide grains MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-04-12 US disclosed
EP-0576910-A1 New radiographic assembly having reduced image-wise cross-over and super rapid processability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-05 EP disclosed
US-5246824-A Gelatin hardened with a vinylsulfone compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-21 US disclosed
EP-0560118-A2 Light-sensitive silver halide photographic element MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-15 EP disclosed
EP-0559061-A2 Method of processing a silver halide radiographic element MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-08 EP disclosed
EP-0497143-A1 Vinylsulfone hardeners MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-05 EP disclosed