SCHEMBL5159157

SCHEMBL5159157

CC(COc1ccccc1Cl)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
POLB P06746 1/20 0.54
CYP1A2 P05177 1/20 0.51
GAA P10253 1/20 0.51
CYP2C19 P33261 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
HPGD P15428 5/20 0.49
HTT P42858 2/20 0.49
TP53 P04637 2/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
USP2 O75604 1/20 0.48
PKM P14618 1/20 0.47
HTR1D P28221 2/20 0.47
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.46
MITF O75030 1/20 0.46
XBP1 P17861 1/20 0.46
NFKB1 P19838 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895849 1.00 MEN1 (0.54) MEN1KMT2APOLBCYP1A2GAA
SCHEMBL5800647 0.81 KMT2A (0.56) MEN1KMT2APOLBHTTHTR1D
SCHEMBL5162157 0.81 TDP1 (0.59) TDP1HPGDSMN1; SMN2TSHR
SCHEMBL21837903 0.80 CYP1A2 (0.51) MEN1KMT2APOLBCYP1A2GAA
SCHEMBL21671283 0.80 CYP1A2 (0.51) MEN1KMT2APOLBCYP1A2GAA
SCHEMBL21837887 0.80 HTR1D (0.53) MEN1KMT2APOLBCYP1A2GAA
SCHEMBL30861819 0.80 HTR1D (0.53) MEN1KMT2APOLBCYP1A2GAA
SCHEMBL21837423 0.80 HTR1D (0.53) MEN1KMT2APOLBCYP1A2GAA
SCHEMBL27730070 0.79 MEN1 (0.57) MEN1KMT2APOLBCYP1A2GAA
SCHEMBL9037793 0.79 MEN1 (0.57) MEN1KMT2APOLBCYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP claimed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US claimed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP claimed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO claimed
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP disclosed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US disclosed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP disclosed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO disclosed