Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.53 |
| ▸ | FNTB | P49356 | 5/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423937 | 0.88 | FNTA (0.59) | FNTAFNTBPGGT1BFOLH1ALDH1A1 | |
| SCHEMBL22100185 | 0.85 | NOD1 (0.43) | FNTAFNTBPGGT1BFOLH1ALDH1A1 | |
| SCHEMBL302151 | 0.85 | FNTA (0.58) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL11413338 | 0.85 | FOLH1 (0.53) | FNTAFNTBPGGT1BFOLH1ALDH1A1 | |
| SCHEMBL753572 | 0.85 | FNTA (0.60) | FNTAFNTBPGGT1BFOLH1ALDH1A1 | |
| SCHEMBL9554921 | 0.85 | FOLH1 (0.53) | FNTAFNTBPGGT1BFOLH1ALDH1A1 | |
| SCHEMBL14554164 | 0.85 | FNTA (0.60) | FNTAFNTBPGGT1BFOLH1ALDH1A1 | |
| SCHEMBL302152 | 0.85 | FNTA (0.58) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL29941368 | 0.85 | GNPAT (0.57) | FNTAFNTBPGGT1BFOLH1ALDH1A1 | |
| SCHEMBL1956539 | 0.84 | FNTA (0.60) | FNTAFNTBPGGT1BNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104438-B1 | NOVEL ANTI-DIABETIC PEPTIDES | AMYLIN PHARMACEUTICALS INC (US) | 2007-02-21 | — | — | EP | disclosed |
| EP-1104438-A2 | NOVEL ANTI-DIABETIC PEPTIDES | AMYLIN PHARMACEUTICALS, INC. (US) | 2001-06-06 | — | — | EP | disclosed |
| US-6087334-A | POLYPEPTIDES AS AN AMYLIN AGONISTS, CALCITONIN AGONISTS, ALSO AS A DRUG FOR REGULATING GASTROINTESTINAL MOTILITY, TREATING DISTURBANCES IN FUEL METABOLISM IN MAMMALS | AMYLIN PHARMACEUTICALS, INC. (US) | 2000-07-11 | — | — | US | disclosed |
| WO-2000011029-A2 | NOVEL ANTI-DIABETIC PEPTIDES | AMYLIN PHARMACEUTICALS, INC. (US) | 2000-03-02 | — | — | WO | disclosed |