SCHEMBL753572

SCHEMBL753572

CSCCCC(=O)N[C@@H](CCSC)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FNTA P49354 5/20 0.60
FNTB P49356 5/20 0.60
PGGT1B P53609 1/20 0.60
FOLH1 Q04609 1/20 0.53
NOD1 Q9Y239 1/20 0.51
MAPK1 P28482 2/20 0.51
LMNA P02545 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
ALDH1A1 P00352 2/20 0.47
USP2 O75604 1/20 0.47
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14554164 1.00 FNTA (0.60) FNTAFNTBPGGT1BFOLH1NOD1
SCHEMBL9830511 0.90 NOD1 (0.60) FNTAFNTBPGGT1BFOLH1NOD1
SCHEMBL9830509 0.90 NOD1 (0.60) FNTAFNTBPGGT1BFOLH1NOD1
SCHEMBL24961510 0.89 FNTA (0.62) FNTAFNTBPGGT1BFOLH1NOD1
SCHEMBL6136379 0.89 NOD1 (0.68) FNTAFNTBPGGT1BNOD1MAPK1
SCHEMBL6136376 0.89 NOD1 (0.68) FNTAFNTBPGGT1BNOD1MAPK1
SCHEMBL4741211 0.87 NOD1 (0.70) FNTAFNTBPGGT1BNOD1MAPK1
SCHEMBL542916 0.87 NOD1 (0.70) FNTAFNTBPGGT1BNOD1MAPK1
SCHEMBL25264982 0.87 NOD1 (0.70) FNTAFNTBPGGT1BNOD1MAPK1
SCHEMBL17204611 0.87 NOD1 (0.70) FNTAFNTBPGGT1BNOD1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623338-B2 Methionine-derived peptidomimetics and their use in the protection of mitochondria of cutaneous cells EXSYMOL S.A.M. (MC) 2014-01-07 US disclosed
EP-2431356-B1 Peptidomimetic methionine derivatives as well as their use in the protection of skin cells EXSYMOL SA (MC) 2013-11-13 EP disclosed
US-20120070394-A1 METHIONINE-DERIVED PEPTIDOMIMETICS AND THEIR USE IN THE PROTECTION OF MITOCHONDRIA OF CUTANEOUS CELLS EXSYMOL S.A.M. (MC) 2012-03-22 US disclosed
EP-2431356-A1 Peptidomimetic methionine derivatives as well as their use in the protection of skin cells Exsymol S.A.M. (MC) 2012-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070394-A1 METHIONINE-DERIVED PEPTIDOMIMETICS AND THEIR USE IN THE PROTECTION OF MITOCHONDRIA OF CUTANEOUS CELLS MTR, ARG2, MARS2 FNTA 4498/4885FNTB 3825/4885PGGT1B 4738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.