Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690940 | 0.89 | IDO1 (0.46) | HCAR2KMT2ARORCADRA2ACYP2D6 | |
| SCHEMBL6272307 | 0.86 | HCAR2 (0.46) | HCAR2KMT2AFFAR1ADRA2AADRA2C | |
| SCHEMBL1357005 | 0.84 | ALDH1A1 (0.39) | HCAR2KMT2AADRA2AADRA2CTAAR1 | |
| SCHEMBL198133 | 0.83 | HCAR2 (0.45) | HCAR2DPP4ADRA2AADRA2CADRA2B | |
| Phosphine SCHEMBL20897413 | 0.80 | CYP2D6 (0.46) | HCAR2DPP4ADRA2AADRA2CADRA2B | |
| Ammonia Solution, Strong SCHEMBL27871924 | 0.80 | HCAR2 (0.44) | HCAR2DPP4ADRA2AADRA2CADRA2B | |
| Hydrochloric Acid SCHEMBL28273439 | 0.80 | ALDH1A1 (0.44) | HCAR2DPP4KMT2AADRA2AADRA2C | |
| SCHEMBL22875947 | 0.79 | TAAR1 (0.40) | HCAR2DPP4FFAR1ADRA2AADRA2C | |
| SCHEMBL104838 | 0.78 | HCAR2 (0.42) | HCAR2DPP4FFAR1ADRA2AADRA2C | |
| SCHEMBL3163758 | 0.78 | HCAR2 (0.42) | HCAR2DPP4FFAR1ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581513-B1 | MULTIFUNCTIONAL CATIONIC PHOTOINITIATORS, THEIR PREPARATION AND USE | SUN CHEMICAL CORP (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1581513-A1 | MULTIFUNCTIONAL CATIONIC PHOTOINITIATORS, THEIR PREPARATION AND USE | Sun Chemical Corporation (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004055000-A1 | MULTIFUNCTIONAL CATIONIC PHOTOINITIATORS, THEIR PREPARATION AND USE | SUN CHEMICAL CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |
| US-5025096-A | Preparation of indole and indole derivatives | MINE SAFETY APPLIANCES COMPANY (US) | 1991-06-18 | — | — | US | disclosed |