Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159508 | 0.89 | HCAR2 (0.43) | ADRA2ARORCCYP2D6KMT2AHCAR2 | |
| SCHEMBL6272307 | 0.76 | HCAR2 (0.46) | ADRA2ACYP2D6KMT2AHCAR2 | |
| SCHEMBL1357005 | 0.74 | ALDH1A1 (0.39) | ADRA2ACYP2D6KMT2AHTTHCAR2 | |
| SCHEMBL29671642 | 0.74 | ADRB2 (0.50) | IDO1TDO2SLC6A4ADRB2SLC6A2 | |
| SCHEMBL198133 | 0.73 | HCAR2 (0.45) | ADRA2ACYP2D6TSHRHCAR2ALDH1A1 | |
| SCHEMBL686394 | 0.72 | IDO1 (0.54) | IDO1TDO2SLC6A4ADRB2SLC6A2 | |
| SCHEMBL9241722 | 0.72 | IDO1 (0.54) | IDO1TDO2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18682149 | 0.72 | IDO1 (0.54) | IDO1TDO2SLC6A4ADRB2SLC6A2 | |
| SCHEMBL15338275 | 0.72 | IDO1 (0.54) | IDO1TDO2SLC6A4ADRB2SLC6A2 | |
| SCHEMBL8111645 | 0.72 | IDO1 (0.60) | IDO1TDO2SLC6A4ADRB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |