SCHEMBL5159657

SCHEMBL5159657

O=C1c2ccccc2C(=O)c2cc(S)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
CDC25B P30305 1/20 0.57
NPC1 O15118 7/20 0.56
RAB9A P51151 7/20 0.56
ALDH1A1 P00352 6/20 0.56
SMN1; SMN2 Q16637 6/20 0.56
MAPK1 P28482 5/20 0.56
TP53 P04637 2/20 0.56
CYP3A4 P08684 2/20 0.56
ELANE P08246 1/20 0.56
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
BCL2 P10415 1/20 0.54
MCL1 Q07820 1/20 0.54
LMNA P02545 4/20 0.50
PLA2G1B P04054 3/20 0.50
ATG4B Q9Y4P1 3/20 0.50
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17493301 0.98 MEN1 (0.55) MEN1KMT2ACDC25BNPC1RAB9A
SCHEMBL5548671 0.93 MAOA (0.50) MEN1KMT2ACDC25BNPC1RAB9A
SCHEMBL16601828 0.83 NPC1 (0.60) MEN1KMT2ACDC25BNPC1RAB9A
SCHEMBL26205089 0.80 MAOA (0.40) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL28260408 0.79 MEN1 (0.92) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL28590582 0.77 MEN1 (0.67) MEN1KMT2ACDC25BNPC1RAB9A
SCHEMBL11262118 0.76 MEN1 (0.57) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL1901249 0.76 MEN1 (1.00) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL29358690 0.76 MEN1 (1.00) MEN1KMT2ACDC25BNPC1RAB9A
Anthraquinone SCHEMBL14943 0.76 MEN1 (1.00) MEN1KMT2ACDC25BNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3205640-B1 MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHINETSU CHEMICAL CO (JP) 2019-05-22 EP disclosed
US-20140135359-A1 METHODS OF DESIGNING, PREPARING, AND USING NOVEL PROTONOPHORES MARTINEAU LOUIS C (CA) 2014-05-15 US disclosed
EP-1341038-B1 Photosensitive resin composition FUJIFILM CORP (JP) 2012-10-24 EP disclosed
CN-1890300-B Polymer electrolytes crosslinked by ultraviolet radiation 3M INNOVATIVE PROPERTIES CO 2010-05-26 CN disclosed
EP-1465010-B1 Positive resist composition FUJIFILM CORP (JP) 2009-10-21 EP disclosed
EP-1215205-B1 Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof SONY DEUTSCHLAND GMBH (DE) 2007-11-21 EP disclosed
EP-1349900-B1 METHODS AND COMPOSITIONS FOR INK JET PRINTING OF PRESSURE SENSITIVE ADHESIVE PATTERNS 3M INNOVATIVE PROPERTIES CO (US) 2007-02-14 EP disclosed
CN-1890300-A Polymer electrolytes crosslinked by ultraviolet radiation 3M INNOVATIVE PROPERTIES CO (US) 2007-01-03 CN disclosed
EP-1692215-A1 POLYMER ELECTROLYTES CROSSLINKED BY ULTRAVIOLET RADIATION 3M Innovative Properties Company (US) 2006-08-23 EP disclosed
US-7060738-B2 Polymer electrolytes crosslinked by ultraviolet radiation 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-13 US disclosed
US-20020128340-A1 Methods and compositions for ink jet printing of pressure sensitive adhesive patterns or films on a wide range of substrates 3M INNOVATIVE PROPERTIES COMPANY 2002-09-12 US disclosed
WO-2002066571-A2 METHODS AND COMPOSITIONS FOR INK JET PRINTING OF PRESSURE SENSITIVE ADHESIVE PATTERNS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-08-29 WO disclosed
US-6197844-B1 Floor finish compositions 3M INNOVATIVE PROPERTIES COMPANY 2001-03-06 US disclosed
CN-1229423-A Floor finish compositions MINNESOTA MINING & MFG (US) 1999-09-22 CN disclosed
EP-0929612-A1 FLOOR FINISH COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-07-21 EP disclosed
WO-1998011168-A1 FLOOR FINISH COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-19 WO disclosed
US-4764452-A BLEND OF MALEIC ACID-STYRENE COPOLYMER, HYDROXYL(OR TETRAHYDROFURFURYL) (METH)ACRYLATE, POLYALKYLENE GLYCOL ACRYLATE AND AN UNSATURATED CARBOXYLATED ESTER TAMURA KAKEN CO., LTD. (JP) 1988-08-16 US disclosed
US-4254209-A Dry planographic plate with light sensitive silicone composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-03-03 US disclosed
US-4198241-A PHOTOINITIATOR, UNSATURATED MONOMER, POLYMERIC BINDER, ETHERIFIED THIOANTHRAQUINONE BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-3953408-A LITHOGRAPHIC PLATES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135359-A1 METHODS OF DESIGNING, PREPARING, AND USING NOVEL PROTONOPHORES UQCRC2, UQCRC1, TIMM50 MEN1 1092/4885KMT2A 3551/4885CDC25B 2647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.