SCHEMBL5159735

SCHEMBL5159735

CC(C(=O)O)C(=O)c1c[nH]cn1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5688401 0.82 KDM4E (0.34)
SCHEMBL5164215 0.82
SCHEMBL5159964 0.79 SMN1; SMN2 (0.32) HCAR3
4-Imidazolecarboxylic Acid SCHEMBL1759996 0.76
SCHEMBL12487300 0.74 CTRB1 (0.37)
4-Imidazolecarboxylic Acid SCHEMBL70915 0.73
4-Imidazolecarboxylic Acid SCHEMBL1436797 0.71
4-Imidazolecarboxylic Acid SCHEMBL10564448 0.71
SCHEMBL5752399 0.71
SCHEMBL2818051 0.70 CA12 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340746-B1 Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives SALTIGO GMBH (DE) 2007-02-28 EP disclosed
EP-1340746-A1 Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives BAYER AG (DE) 2003-09-03 EP disclosed