Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158631 | 0.80 | HDAC3 (0.36) | — | |
| SCHEMBL5159735 | 0.79 | HCAR3 (0.30) | HCAR3 | |
| SCHEMBL5158618 | 0.77 | GPR84 (0.33) | HCAR3 | |
| SCHEMBL5164215 | 0.76 | — | — | |
| SCHEMBL4483981 | 0.76 | — | — | |
| SCHEMBL5688401 | 0.76 | KDM4E (0.34) | — | |
| 4-Imidazolecarboxylic Acid SCHEMBL14742159 | 0.74 | HCAR2 (0.32) | HCAR3 | |
| 4-Imidazolecarboxylic Acid SCHEMBL70915 | 0.71 | — | — | |
| SCHEMBL4919462 | 0.70 | — | — | |
| SCHEMBL31554349 | 0.70 | AKR1C3 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |