SCHEMBL5159958

SCHEMBL5159958

C=Cc1ccnc2c1ccc1cccnc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 6/20 0.57
CCR8 P51685 6/20 0.57
L3MBTL1 Q9Y468 5/20 0.57
CCR5 P51681 4/20 0.57
LMNA P02545 4/20 0.55
KDM4E B2RXH2 4/20 0.55
MAPT P10636 4/20 0.55
MMP2 P08253 2/20 0.55
TSHR P16473 2/20 0.55
CYP3A4 P08684 2/20 0.55
HSP90AA1 P07900 2/20 0.55
HTT P42858 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
GMNN O75496 1/20 0.55
TP53 P04637 1/20 0.55
CYP2D6 P10635 1/20 0.55
MMP9 P14780 1/20 0.55
ALOX15 P16050 1/20 0.55
NFKB1 P19838 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10985905 0.85 CCR1 (0.61) CCR1CCR8L3MBTL1CCR5KDM4E
SCHEMBL7749185 0.83 CCR1 (0.72) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL11888289 0.83 CCR1 (0.43) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL10986683 0.79 LMNA (0.53) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL7749257 0.79 CCR1 (0.53) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL7749251 0.79 CCR1 (0.53) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL2129888 0.76 KDM4E (0.54) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL12533508 0.76 CCR1 (0.53) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL23519813 0.75 KDM4E (0.54) CCR1CCR8L3MBTL1CCR5LMNA
SCHEMBL20726958 0.75 LMNA (0.55) CCR1CCR8L3MBTL1CCR5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023052225-A1 MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2023-04-06 WO claimed
WO-2023052225-A1 MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2023-04-06 WO disclosed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP disclosed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP disclosed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP disclosed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 US disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US disclosed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed
US-4524114-A Bifunctional air electrode ALLIED CORPORATION (US) 1985-06-18 US disclosed