Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243930 | 0.84 | KDM4E (0.50) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL6847746 | 0.80 | KDM4E (0.50) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL6850791 | 0.80 | KDM4E (0.50) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL216372 | 0.79 | KDM4E (0.54) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL194281 | 0.79 | KDM4E (0.54) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL24060233 | 0.79 | KDM4E (0.54) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL16309644 | 0.79 | KDM4E (0.48) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL20726958 | 0.79 | LMNA (0.55) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL23519813 | 0.79 | KDM4E (0.54) | KDM4EMAPTLMNATDP1MMP2 | |
| SCHEMBL26115261 | 0.79 | KDM4E (0.43) | KDM4EMAPTLMNATDP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562116-B2 | Method for preparation of ruthenium-based metathesis catalysts with chelating alkylidene ligands | UMICORE AG & CO. KG (DE) | 2017-02-07 | — | — | US | claimed |
| CN-102481557-B | Method for preparation of ruthenium-based metathesis catalysts with chelating alkylidene ligands | UMICORE AG & CO KG | 2015-04-01 | — | — | CN | claimed |
| US-20140371462-A1 | METHOD FOR PREPARATION OF RUTHENIUM-BASED METATHESIS CATALYSTS WITH CHELATING ALKYLIDENE LIGANDS | UMICORE AG & CO KG (DE) | 2014-12-18 | — | — | US | claimed |
| US-8846938-B2 | Method for preparation of ruthenium-based metathesis catalysts with chelating alkylidene ligands | UMICORE AG & CO. KG (DE) | 2014-09-30 | — | — | US | claimed |
| EP-2255877-B1 | Method for preparation of ruthenium-based metathesis catalysts with chelating alkylidene ligands | UMICORE AG & CO KG (DE) | 2014-09-24 | — | — | EP | claimed |
| US-8658796-B2 | Complexes of ruthenium, method of production thereof and use thereof as (pre)catalysts of the metathesis reaction | UMICORE AG & CO. KG (DE) | 2014-02-25 | — | — | US | claimed |
| US-20130079515-A1 | Complexes of Ruthenium, Method of Production Thereof And Use Thereof As (Pre)Catalysts of the Metathesis Reaction | UMICORE AG & CO. KG (DE) | 2013-03-28 | — | — | US | claimed |
| US-8318965-B2 | Complex of ruthenium, method of production thereof and use thereof as (pre)catalysts of the metathesis reaction | UMICORE AG & CO. KG (DE) | 2012-11-27 | — | — | US | claimed |
| EP-2029278-B1 | COMPLEX OF RUTHENIUM, METHOD OF PRODUCTION THEREOF AND USE THEREOF AS (PRE)CATALYST OF THE METATHESIS REACTION | UMICORE AG & CO KG (DE) | 2012-10-24 | — | — | EP | claimed |
| CN-102481557-A | Process for preparing ruthenium-based metathesis catalysts with chelating alkylidene ligands | UMICORE AG & CO KG | 2012-05-30 | — | — | CN | claimed |
| US-20120101279-A1 | METHOD FOR PREPARATION OF RUTHENIUM-BASED METATHESIS CATALYSTS WITH CHELATING ALKYLIDENE LIGANDS | UMICORE AG & CO. KG (DE) | 2012-04-26 | — | — | US | claimed |
| EP-2255877-A1 | Method for preparation of ruthenium-based metathesis catalysts with chelating alkylidene ligands | Umicore AG & Co. KG (DE) | 2010-12-01 | — | — | EP | claimed |
| WO-2010127829-A1 | METHOD FOR PREPARATION OF RUTHENIUM-BASED METATHESIS CATALYSTS WITH CHELATING ALKYLIDENE LIGANDS | UMICORE AG & CO. KG (DE) | 2010-11-11 | — | — | WO | claimed |
| US-20250177965-A1 | HETEROGENEOUS CATALYSTS AND METHODS MAKING AND USING THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2025-06-05 | — | — | US | disclosed |
| CN-120054643-A | Heterogeneous catalysts and methods of making and using the same | 香港大学 | 2025-05-30 | — | — | CN | disclosed |
| US-20250122133-A1 | Selective Transition Metal Catalyzed Deuterium Incorporation Into Alkyne and Alkene Functionalities | MARQUETTE UNIVERSITY | 2025-04-17 | — | — | US | disclosed |
| WO-2008000644-A1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METAHESIS REACTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |
| CN-1100414-A | Preparation of pharmaceutical compound containing novel derivative of leukol | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-03-22 | — | — | CN | disclosed |
| CN-1027368-C | Process for preparing substituted quinoline derivatives | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-01-11 | — | — | CN | disclosed |
| CN-1035501-A | PROCESS FOR PREPARING SUBSTITUTED QUINOLINE DERIVATIVES | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-09-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122133-A1 | Selective Transition Metal Catalyzed Deuterium Incorporation Into Alkyne and Alkene Functionalities | HDHD5, DDT, AHR | KDM4E 2682/4885MAPT 4366/4885LMNA 2028/4885 |
| US-20120101279-A1 | METHOD FOR PREPARATION OF RUTHENIUM-BASED METATHESIS CATALYSTS WITH CHELATING ALKYLIDENE LIGANDS | HMOX2, TIMCC, HPD | KDM4E 2430/4885MAPT 4290/4885LMNA 2907/4885 |
| US-20130079515-A1 | Complexes of Ruthenium, Method of Production Thereof And Use Thereof As (Pre)Catalysts of the Metathesis Reaction | CBR3, CBR1, C1R | KDM4E 2452/4885MAPT 4787/4885LMNA 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.