⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269579 | 1.00 | — | — | |
| SCHEMBL8811486 | 0.91 | LMNA (0.39) | — | |
| SCHEMBL8811527 | 0.91 | LMNA (0.39) | — | |
| SCHEMBL8760269 | 0.87 | — | — | |
| SCHEMBL17143810 | 0.84 | — | — | |
| SCHEMBL1410494 | 0.84 | — | — | |
| SCHEMBL17143522 | 0.84 | — | — | |
| SCHEMBL17143627 | 0.82 | LMNA (0.35) | — | |
| SCHEMBL1410630 | 0.82 | LMNA (0.35) | — | |
| SCHEMBL4100336 | 0.82 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070207948-A1 | Convergent Synthesis for Kahalalide Compounds | PHARMA MAR, S.A.U. (ES) | 2007-09-06 | — | — | US | claimed |
| EP-1749023-A1 | CONVERGENT SYNTHESIS FOR KAHALALIDE COMPOUNDS | Pharma Mar, S.A.U. (ES) | 2007-02-07 | — | — | EP | claimed |
| WO-2005103072-A1 | CONVERGENT SYNTHESIS FOR KAHALALIDE COMPOUNDS | PHARMA MAR, S.A.U. (ES) | 2005-11-03 | — | — | WO | claimed |
| US-20070207948-A1 | Convergent Synthesis for Kahalalide Compounds | PHARMA MAR, S.A.U. (ES) | 2007-09-06 | — | — | US | disclosed |
| EP-1749023-A1 | CONVERGENT SYNTHESIS FOR KAHALALIDE COMPOUNDS | Pharma Mar, S.A.U. (ES) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005103072-A1 | CONVERGENT SYNTHESIS FOR KAHALALIDE COMPOUNDS | PHARMA MAR, S.A.U. (ES) | 2005-11-03 | — | — | WO | disclosed |