SCHEMBL5160157

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5159848	0.86	MEN1 (0.39)	SLC6A3PTGS2SLC6A2MEN1KMT2A
	SCHEMBL5158439	0.78	CHRNB4 (0.41)	SLC6A2SMN1; SMN2ALDH1A1MEN1MAPT
	SCHEMBL5159946	0.77	KIF11 (0.40)	PTGS2ALDH1A1MAPTPTGS1SLC6A4
	SCHEMBL5160367	0.75	CHRNA7 (0.33)	CYP2D6KDM4ECYP1A2ALDH1A1MEN1
	SCHEMBL5159838	0.69	TAAR1 (0.36)	SLC6A3SLC6A2CYP2D6CYP1A2MEN1
	SCHEMBL5158346	0.68	TSHR (0.34)	SLC6A3SLC6A2CYP2D6ALDH1A1CYP2C19
	SCHEMBL5158203	0.68	GAA (0.35)	SLC6A3CYP2D6KDM4EALDH1A1MEN1
	SCHEMBL27310296	0.68	PTGS2 (0.39)	SLC6A3PTGS2SLC6A2SMN1; SMN2CYP2D6
	Hydrochloric Acid SCHEMBL5159700	0.68	TAAR1 (0.35)	SLC6A3SLC6A2CYP2D6CYP1A2MEN1
	SCHEMBL5160399	0.67	KMT2A (0.35)	SLC6A3SMN1; SMN2CYP2D6KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.