Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 8/20 | 0.49 |
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243772 | 1.00 | ACE (0.58) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL7014593 | 1.00 | ACE (0.58) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL23574413 | 0.93 | ACE (0.52) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL23574224 | 0.93 | ACE (0.52) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL23574222 | 0.93 | ACE (0.52) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL23574414 | 0.93 | ACE (0.52) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL7270069 | 0.92 | ACE (0.58) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL8417806 | 0.91 | THRB (0.59) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL1526069 | 0.91 | THRB (0.59) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL10780803 | 0.91 | THRB (0.59) | ACEITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271009-B1 | Multi-analyte diagnostic test for thyroid disorders | BIO-RAD LABORATORIES, INC. (US) | 2007-09-18 | — | — | US | claimed |
| EP-1272855-B1 | MULTI-ANALYTE DIAGNOSTIC TEST FOR THYROID DISORDERS | BIO RAD LABORATORIES (US) | 2007-06-06 | — | — | EP | claimed |
| US-20030054571-A1 | Multi-analyte diagnostic test for thyroid disorders | BIO-RAD LABORATORIES, INC. (US) | 2003-03-20 | — | — | US | claimed |
| EP-1272855-A2 | MULTI-ANALYTE DIAGNOSTIC TEST FOR THYROID DISORDERS | BIO-RAD LABORATORIES, INC. (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079844-A2 | MULTI-ANALYTE DIAGNOSTIC TEST FOR THYROID DISORDERS | BIO-RAD LABORATORIES, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| US-5767158-A | FOR BLEACHING SKIN | SHISEIDO CO., LTD. (JP) | 1998-06-16 | — | — | US | claimed |
| US-20250345488-A1 | CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4371982-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-3583096-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2024-03-27 | — | — | EP | disclosed |
| US-20240057599-A1 | METHODS FOR IMPROVING FRUIT QUALITY | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2024-02-22 | — | — | US | disclosed |
| US-20240049709-A1 | METHOD OF CONTROLLING FUNGAL INFECTIONS IN PLANTS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O), THE VOLCANI INSTITUTE (IL) | 2024-02-15 | — | — | US | disclosed |
| US-11812746-B2 | Method of controlling fungal infections in plants | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2023-11-14 | — | — | US | disclosed |
| US-20230133667-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| EP-0728469-A2 | An endermic liniment | SHISEIDO COMPANY LIMITED (JP) | 1996-08-28 | — | — | EP | disclosed |
| WO-1996022305-A2 | MODIFIED PEPTIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-25 | — | — | WO | disclosed |
| US-5433940-A | Synthetic molecules mimic action of hirudin by binding to both the low affinity anion-binding exosite and the catalytic site of thrombin | BIOGEN, INC. (US) | 1995-07-18 | — | — | US | disclosed |
| US-5196404-A | Hirudin mimic, polypeptide, hirulog; bivalirudin FDA Orange book listed patent | BIOGEN, INC. (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0489070-A1 | NOVEL INHIBITORS OF THROMBIN. | BIOGEN INC (US) | 1992-06-10 | — | — | EP | disclosed |
| WO-1991002750-A1 | NOVEL INHIBITORS OF THROMBIN | BIOGEN, INC. (US) | 1991-03-07 | — | — | WO | disclosed |
| EP-0403828-A1 | Renin-inhibiting peptides, their preparation and their use in medicaments | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133667-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | ACE 170/4885ITGB3 4676/4885ITGA2B 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.