Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.64 |
| ▸ | DRD2 | P14416 | 7/20 | 0.64 |
| ▸ | DRD3 | P35462 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HTR1B | P28222 | 2/20 | 0.62 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11894824 | 0.94 | KCNA3 (0.64) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL8725186 | 0.94 | DRD4 (0.61) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL11895679 | 0.92 | KCNA3 (0.61) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL11639590 | 0.92 | KCNA3 (0.61) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL11675936 | 0.91 | DRD4 (0.55) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL10410538 | 0.87 | DRD2 (0.68) | DRD4DRD2DRD3MAPTHTR1B | |
| SCHEMBL11675915 | 0.86 | KCNA3 (0.53) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL10411052 | 0.86 | PPARG (0.73) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL10409542 | 0.84 | DRD2 (0.51) | DRD4DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL11445655 | 0.83 | PKM (0.65) | DRD4DRD2DRD3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000107-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | claimed |
| US-9000107-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| EP-1790337-A2 | Methods and compounds for treating depression and other disorders | NPS PHARMACEUTICALS, INC. (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1096926-B1 | METHODS AND COMPOUNDS FOR TREATING DEPRESSION | NPS PHARMA INC (US) | 2007-02-28 | — | — | EP | disclosed |