SCHEMBL51604

SCHEMBL51604

Oc1ccc(Cl)cc1C(c1ccccc1)c1cc(Cl)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
MAPT P10636 4/20 0.50
HPGD P15428 4/20 0.50
LMNA P02545 3/20 0.50
MAPK1 P28482 3/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
HTT P42858 4/20 0.48
NPSR1 Q6W5P4 3/20 0.48
CYP3A4 P08684 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
GAA P10253 1/20 0.48
THRB P10828 1/20 0.48
HSD17B10 Q99714 3/20 0.44
ALOX15 P16050 2/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295105 0.96 MEN1 (0.54) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL51321 0.85 TYR (0.44) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL30443320 0.83 MEN1 (0.53) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL4627114 0.83 MEN1 (0.53) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL3831831 0.81 MEN1 (0.51) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL574405 0.81 KMT2A (0.59) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL51791 0.80 TYR (0.52) KMT2ALMNAHTTCYP1A2CYP2C9
SCHEMBL26999265 0.78 MAPT (0.48) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL4066948 0.77 ESR2 (0.41) HPGDLMNACYP3A4HSD17B10TSHR
SCHEMBL51095 0.77 CHRM1 (0.55) MEN1KMT2AMAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8129307-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-03-06 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
EP-2112001-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries CO., LTD. (JP) 2009-10-28 EP disclosed