SCHEMBL51321

SCHEMBL51321

Oc1cc(Cl)ccc1C(c1ccccc1)c1ccc(Cl)cc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.44
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
HSD17B10 Q99714 4/20 0.43
CYP3A4 P08684 3/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HPGD P15428 3/20 0.41
ALOX15 P16050 2/20 0.41
HIF1A Q16665 1/20 0.41
LMNA P02545 2/20 0.40
MAPK1 P28482 2/20 0.40
MAPT P10636 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
CASP3 P42574 1/20 0.40
SENP7 Q9BQF6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758126 0.90 HSD17B10 (0.48) IDO1TDO2HSD17B10CYP3A4TSHR
SCHEMBL51604 0.85 MEN1 (0.54) IDO1TDO2HSD17B10CYP3A4TSHR
SCHEMBL28220955 0.83 TYR (0.43) TYRIDO1TDO2HSD17B10CYP3A4
SCHEMBL30327120 0.83 LMNA (0.40) TYRIDO1TDO2CYP3A4TSHR
SCHEMBL28295105 0.81 MEN1 (0.54) IDO1TDO2HSD17B10CYP3A4TSHR
SCHEMBL84243 0.80 TYR (0.67) TYRALDH1A1TDP1KMT2A
SCHEMBL50970 0.77 TRPA1 (0.57) TYRIDO1TDO2ALDH1A1MEN1
SCHEMBL51614 0.77 ALOX5 (0.55) TYRHSD17B10CYP3A4ALDH1A1MEN1
SCHEMBL22051079 0.77 TYR (0.44) TYRHSD17B10CYP3A4TSHRALDH1A1
SCHEMBL4066948 0.77 ESR2 (0.41) TYRHSD17B10CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed