Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472585 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| SCHEMBL28553323 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| SCHEMBL28824246 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| SCHEMBL4465282 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| SCHEMBL7273343 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL11601052 | 0.98 | DNM1 (0.48) | EPHX2DNM1AKR1B1KDM5AKDM5C | |
| SCHEMBL9700493 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| SCHEMBL14763563 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| SCHEMBL5395582 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD | |
| SCHEMBL4874900 | 0.98 | EPHX2 (0.51) | EPHX2DNM1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829547-A | Factor XIIa inhibitors | 卡尔维斯塔制药有限公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-3852746-A1 | CYCLOPENTYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3728240-A1 | ISOXAZOLE O-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-10-28 | — | — | EP | disclosed |
| WO-2020060915-A1 | CYCLOPENTYL ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-26 | — | — | WO | disclosed |
| EP-3200797-A1 | QUINAZOLINE-BASED KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016053794-A1 | QUINAZOLINE-BASED KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-04-07 | — | — | WO | disclosed |
| US-20120027824-A1 | Preparations facilitated by vesicles using alkyl polypentosides and uses of said preparations | AGRO INDUSTRIE RECHERCHES ET DEVELOPPEMENT (A.R.D.) (FR) | 2012-02-02 | — | — | US | disclosed |
| EP-2380658-A2 | Easier vesicle preparations using alkyl poly-pentosides and use of said preparations | Agro Industrie Recherches Et Developpements A.R.D. (FR) | 2011-10-26 | — | — | EP | disclosed |
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-1756037-A2 | AMINO ALCOHOL DERIVATIVES AND THEIR ACTIVITY AS RENIN INHIBITORS | Speedel Experimenta AG (CH) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005070871-A2 | AMINO ALCOHOL DERIVATIVES AND THEIR ACTIVITY AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2005-08-04 | — | — | WO | disclosed |
| EP-0033098-B1 | N-METHYL-N-SILYL-CARBAMATES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BASF Aktiengesellschaft (DE) | 1983-11-23 | — | — | EP | disclosed |
| US-4360517-A | INSECTICIDES, MITICIDES, AND NEMATOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| EP-0008651-B1 | DERIVATIVES OF TRIAZOLE, PROCESS FOR THEIR PRODUCTION AND INSECTICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0033098-A2 | N-methyl-N-silyl-carbamates, processes for their preparation and their use as pesticides | BASF Aktiengesellschaft (DE) | 1981-08-05 | — | — | EP | disclosed |
| EP-0008651-A1 | Derivatives of triazole, process for their production and insecticides containing them | BASF Aktiengesellschaft (DE) | 1980-03-19 | — | — | EP | disclosed |
| EP-0007589-A1 | Insecticide agents comprising carbamate as active ingredient and triazole derivatives as synergists | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | EPHX2 1413/4885DNM1 3685/4885AKR1B1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.