Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404243 | 0.86 | TSHR (0.40) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL515117 | 0.81 | TSHR (0.44) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL418249 | 0.80 | LMNA (0.38) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL3660480 | 0.76 | LMNA (0.39) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL3657152 | 0.74 | LMNA (0.37) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL402954 | 0.74 | TSHR (0.40) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL3658972 | 0.74 | LMNA (0.37) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL10266665 | 0.74 | MAPK1 (0.38) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL2120447 | 0.74 | MAPK1 (0.38) | SMN1; SMN2LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL401990 | 0.74 | PTGDR (0.36) | MAPK1CYP1A2SRD5A1EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393769-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2014-12-10 | — | — | EP | disclosed |
| US-8680339-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| CN-102361846-A | Novel herbicides | SYNGENTA LTD | 2012-02-22 | — | — | CN | disclosed |
| US-20120028800-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| EP-2393769-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089210-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028800-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | SMN1; SMN2 2952/4885LMNA 4657/4885HPGD 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.