SCHEMBL5160940

SCHEMBL5160940

CC1=C(Cl)C(=O)C(C)C(N)(Cl)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11656294 0.60
SCHEMBL9650954 0.57
SCHEMBL28647953 0.50 CES2 (0.38)
SCHEMBL20867386 0.50 CES2 (0.53)
SCHEMBL5588953 0.50 KDM4E (0.47)
SCHEMBL13906871 0.50 MAPT (0.32)
SCHEMBL2575338 0.50 CES1 (0.57)
SCHEMBL1392670 0.50 CES1 (0.47)
SCHEMBL4072850 0.50 MAPT (0.32)
SCHEMBL23833715 0.49

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754514-A1 Agent and method for colouring keratin fibres Wella Aktiengesellschaft (DE) 2007-02-21 EP claimed
US-20070000073-A1 Agent and method for colouring keratin fibres PROCTER & GAMBLE COMPANY, THE 2007-01-04 US claimed
WO-2006094217-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES THE PROCTER & GAMBLE COMPANY (US) 2006-09-08 WO claimed
US-7070625-B2 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives WELLA AG (DE) 2006-07-04 US claimed
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2004-04-01 US claimed
EP-1754514-A1 Agent and method for colouring keratin fibres Wella Aktiengesellschaft (DE) 2007-02-21 EP disclosed
US-20070000073-A1 Agent and method for colouring keratin fibres PROCTER & GAMBLE COMPANY, THE 2007-01-04 US disclosed
WO-2006094217-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES THE PROCTER & GAMBLE COMPANY (US) 2006-09-08 WO disclosed
US-7070625-B2 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives WELLA AG (DE) 2006-07-04 US disclosed
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2004-04-01 US disclosed
EP-0246112-B1 PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS THE DOW CHEMICAL COMPANY (US) 1991-06-12 EP disclosed
US-4806688-A Preparation of diamino- and dialkylaminobenzenediols THE DOW CHEMICAL COMPANY (US) 1989-02-21 US disclosed
EP-0246112-A1 Preparation of diamino- and dialkylaminobenzenediols THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
WO-1987006930-A1 PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS THE DOW CHEMICAL COMPANY (US) 1987-11-19 WO disclosed