SCHEMBL4072850

SCHEMBL4072850

CC1=C(C)C(=O)C(C)C(C)C1=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201480 0.83
SCHEMBL14084133 0.79
SCHEMBL12670167 0.79
SCHEMBL16379923 0.78 MAPT (0.31) MAPTKDM4ETP53MAPK1CYP2C19
SCHEMBL13906871 0.77 MAPT (0.32) MAPTKDM4ETP53MAPK1CYP2C19
SCHEMBL14870738 0.72
SCHEMBL14953626 0.67
SCHEMBL14924209 0.67 MEN1 (0.33)
SCHEMBL20269228 0.65 MAPT (0.36) MAPTKDM4ETP53MAPK1CYP2C19
SCHEMBL20269881 0.65 MAPT (0.36) MAPTKDM4ETP53MAPK1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312785-A1 N-TYPE CONJUGATED POLYMERS AND BLENDS, AND METHOD FOR PREPARING THE SAME AND APPLICATION SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2023-10-05 US disclosed
EP-2609079-B1 PROCESS FOR THE MANUFACTURE OF TMHQ DSM IP ASSETS BV (NL) 2015-05-06 EP disclosed
US-8809591-B2 Process for the manufacture of TMHQ DSM IP ASSETS B.V. (NL) 2014-08-19 US disclosed
US-8802398-B2 Oxidation process DUPONT NUTRITION BIOSCIENCES APS (DK) 2014-08-12 US disclosed
US-8802398-B2 Oxidation process DUPONT NUTRITION BIOSCIENCES APS (DK) 2014-08-12 US disclosed
US-8791232-B2 Proteins DUPONT NUTRITION BIOSCIENCES APS (DK) 2014-07-29 US disclosed
US-8791232-B2 Proteins DUPONT NUTRITION BIOSCIENCES APS (DK) 2014-07-29 US disclosed
US-20130211080-A1 PROCESS FOR THE MANUFACTURE OF TMHQ DSM IP ASSETS B.V. (NL) 2013-08-15 US disclosed
US-20110256571-A1 PROTEINS DUPONT NUTRITION BIOSCIENCES APS (DK) 2011-10-20 US disclosed
US-20110256571-A1 PROTEINS DUPONT NUTRITION BIOSCIENCES APS (DK) 2011-10-20 US disclosed
US-20110236935-A1 OXIDATION PROCESS DUPONT NUTRITION BIOSCIENCES APS (DK) 2011-09-29 US disclosed
US-20110236935-A1 OXIDATION PROCESS DUPONT NUTRITION BIOSCIENCES APS (DK) 2011-09-29 US disclosed
EP-2084227-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-08-05 EP disclosed
WO-2008063724-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110256571-A1 PROTEINS PHAX, UPF1, YIF1A MAPT 3220/4885KDM4E 3158/4885TP53 1346/4885
US-20130211080-A1 PROCESS FOR THE MANUFACTURE OF TMHQ POLQ, PNMT, TERT MAPT 1208/4885KDM4E 347/4885TP53 2505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.