Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732583 | 0.89 | OPRM1 (0.38) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 | |
| SCHEMBL6937453 | 0.84 | SLC6A4 (0.46) | OPRM1OPRK1OPRD1SLC6A4KDR | |
| SCHEMBL6937006 | 0.84 | MEN1 (0.34) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 | |
| SCHEMBL5159940 | 0.84 | OPRM1 (0.40) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 | |
| SCHEMBL6941375 | 0.82 | OPRM1 (0.41) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 | |
| SCHEMBL6938750 | 0.80 | OPRM1 (0.40) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 | |
| SCHEMBL6939122 | 0.80 | TACR1 (0.35) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 | |
| SCHEMBL5163165 | 0.80 | OPRM1 (0.44) | OPRM1OPRL1SLC6A9OPRK1OPRD1 | |
| SCHEMBL2357274 | 0.79 | SLC6A4 (0.35) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 | |
| SCHEMBL6939344 | 0.79 | OPRL1 (0.45) | OPRM1OPRL1SLC6A9SLC6A5OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406857-B1 | SUBSTITUTED 1-ARYL-BUT-3-ENYLAMINE AND 1-ARYL-BUT-2-ENYLAMINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2007-02-21 | — | — | EP | disclosed |