⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298741 | 0.84 | — | — | |
| Fluoride SCHEMBL29252244 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27848519 | 0.82 | — | — | |
| SCHEMBL17675426 | 0.81 | — | — | |
| SCHEMBL7275301 | 0.79 | — | — | |
| SCHEMBL28042239 | 0.78 | CYP1A2 (0.30) | — | |
| SCHEMBL371279 | 0.76 | GNAI3 (0.33) | — | |
| SCHEMBL7121806 | 0.75 | — | — | |
| SCHEMBL21427427 | 0.75 | — | — | |
| SCHEMBL249356 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040581-A1 | NOVEL QUINOLINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | 고려대학교 산학협력단 | 2020-02-27 | — | — | WO | claimed |
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| US-20230365549-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALING PATHWAY | REDX PHARMA PLC (GB) | 2023-11-16 | — | — | US | disclosed |
| US-11643408-B2 | N-pyridinyl acetamide derivatives as inhibitors of the WNT signaling pathway | REDX PHARMA PLC (GB) | 2023-05-09 | — | — | US | disclosed |
| EP-3204378-B3 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2022-05-25 | — | — | EP | disclosed |
| US-20210046076-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALING PATHWAY | REDX PHARMA PLC (GB) | 2021-02-18 | — | — | US | disclosed |
| US-10793560-B2 | N-pyridinyl acetamide derivatives as inhibitors of the WNT signaling pathway | REDX PHARMA PLC (GB) | 2020-10-06 | — | — | US | disclosed |
| WO-2020040581-A1 | NOVEL QUINOLINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | 고려대학교 산학협력단 | 2020-02-27 | — | — | WO | disclosed |
| US-20190330198-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-31 | — | — | US | disclosed |
| CN-107108565-B | The N- pyridine yl acetamide derivatives of inhibitor as WNT signal transmission approach | 莱德克斯制药公共有限公司 | 2019-08-23 | — | — | CN | disclosed |
| WO-2016055786-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2016-04-14 | — | — | WO | disclosed |
| CN-103772345-B | A kind of preparation method of fluorinated ethylene carbonate | SUZHOU FUTE BATTERY MATERIAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| US-8124605-B2 | Compositions and methods for modulating a kinase cascade | KINEX PHARMACEUTICALS, LLC (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090149510-A1 | Compositions and methods for modulating a kinase cascade | OAKTREE FUND ADMINISTRATION, LLC | 2009-06-11 | — | — | US | disclosed |
| CN-101022813-A | Pyridine derivatives of indolin-2-ones, process for their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2007-08-22 | — | — | CN | disclosed |
| EP-1373323-B1 | CO2-TERMINATED RUBBER | FIRESTONE POLYMERS LLC (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1373323-A1 | CO2-TERMINATED RUBBER | Firestone Polymers, LLC (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079267-A1 | CO2-TERMINATED RUBBER | FIRESTONE POLYMERS, LLC (US) | 2002-10-10 | — | — | WO | disclosed |
| US-6316577-B1 | PHOTOSENSITIVITY AND DURABILITY; | HODOGAYA CHEMICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-4373176-A | ELECTROLYTE IS A TERTIARY AMINE OR DIPROPYLAMINE MONO SALT OF DODECANEDIOIC ACID | SPRAGUE ELECTRIC COMPANY (US) | 1983-02-08 | — | — | US | disclosed |