SCHEMBL371279

SCHEMBL371279

CCCCCN1C=CCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33
GNAI1 P63096 2/20 0.33
NPC1 O15118 6/20 0.32
RAB9A P51151 6/20 0.32
HTT P42858 5/20 0.32
LMNA P02545 3/20 0.32
ALDH1A1 P00352 3/20 0.32
APOBEC3A P31941 2/20 0.32
APOBEC3G Q9HC16 2/20 0.32
PABPC1 P11940 1/20 0.32
ALOX5 P09917 2/20 0.32
GALR3 O60755 2/20 0.32
POLB P06746 2/20 0.32
ATM Q13315 2/20 0.32
MAPK1 P28482 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5992845 0.94 LTA4H (0.33) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL28042239 0.94 CYP1A2 (0.30) CYP1A2CYP2D6
SCHEMBL11355995 0.91 LTA4H (0.35) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL5174927 0.88 GNAI3 (0.35) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL23912452 0.86 GNAI3 (0.38) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL27451155 0.86 GNAI3 (0.38) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL27616893 0.86 GNAI3 (0.34) GNAI3GNAO1GNAI1NPC1RAB9A
Bromide SCHEMBL29130097 0.86 NPC1 (0.36) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL28287505 0.86 GNAI3 (0.38) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL28282304 0.86 GNAI3 (0.38) GNAI3GNAO1GNAI1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024048778-A1 ARYLTETRAHYDROPYRIDINE COMPOUND AND PEST CONTROL AGENT 日産化学株式会社 2024-03-07 WO claimed
US-6362009-B1 CAPTURING A SUBSTRATE ON SOLID SUPPORT AND ACTIVATINGSUBSTRATE TO REACT WITH REAGENT WITH WHICH UNACTIVATED SUBSTRATE DOES NOT REACT; REACTING ACTIVATED SUBSTRATE ON SOLID PHASE WITH REAGENT TO GIVE AN ADDITION PRODUCT MERCK & CO., INC. 2002-03-26 US claimed
JP-11335376-A None JP disclosed
WO-2024048778-A1 ARYLTETRAHYDROPYRIDINE COMPOUND AND PEST CONTROL AGENT 日産化学株式会社 2024-03-07 WO disclosed
WO-2024048778-A1 ARYLTETRAHYDROPYRIDINE COMPOUND AND PEST CONTROL AGENT 日産化学株式会社 2024-03-07 WO disclosed
US-20230295108-A1 ARYLTETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF NIHON NOHYAKU CO., LTD. (JP) 2023-09-21 US disclosed
WO-2023127806-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 日本農薬株式会社 2023-07-06 WO disclosed
EP-4174056-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, INSECTICIDE CONTAINING SAME, AND METHOD FOR USE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2023-05-03 EP disclosed
CN-115916752-A Aryltetrahydropyridine derivatives or salts thereof, and pesticides containing the same and methods of use thereof 日本农药株式会社 2023-04-04 CN disclosed
CN-115916752-A Aryltetrahydropyridine derivatives or salts thereof, and pesticides containing the same and methods of use thereof 日本农药株式会社 2023-04-04 CN disclosed
EP-3022180-B1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF CORAL SUNSCREEN PTY LTD (AU) 2022-02-23 EP disclosed
WO-1992012975-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR COTININE ABBOTT LABORATORIES (US) 1992-08-06 WO disclosed
US-5134150-A Administering diaryl-substituted imidazothiazoles; antiarthritic agents SMITHKLINE BEECHAM CORPORATION (US) 1992-07-28 US disclosed
EP-0321490-A4 INHIBITION OF INTERLEUKIN-1 PRODUCTION BY MONOCYTES AND/OR MACROPHAGES. SMITHKLINE BECKMAN CORP (US) 1990-05-14 EP disclosed
EP-0321490-A1 INHIBITION OF INTERLEUKIN-1 PRODUCTION BY MONOCYTES AND/OR MACROPHAGES. SMITHKLINE BECKMAN CORP (US) 1989-06-28 EP disclosed
WO-1988001169-A1 INHIBITION OF INTERLEUKIN-1 PRODUCTION BY MONOCYTES AND/OR MACROPHAGES SMITHKLINE BECKMAN CORPORATION (US) 1988-02-25 WO disclosed
EP-0231622-A2 Inhibition of the 5-lipoxygenase pathway SMITHKLINE BEECHAM CORPORATION (US) 1987-08-12 EP disclosed
US-4320137-A Derivatives of perhydro-aza-heterocycles CIBA-GEIGY CORPORATION (US) 1982-03-16 US disclosed
US-4246269-A Antidepressant piperidinones CIBA-GEIGY CORPORATION (US) 1981-01-20 US disclosed
US-4160837-A ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1979-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295108-A1 ARYLTETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF TRPA1, DDT, HPD GNAI3 2551/4885GNAO1 1227/4885GNAI1 2060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.