Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162759 | 0.82 | DRD2 (0.50) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL5160962 | 0.81 | KDM4E (0.62) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL30790269 | 0.79 | FLT3 (0.65) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL2605497 | 0.79 | FLT3 (0.65) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL5160307 | 0.79 | KDM4E (0.58) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL5162750 | 0.77 | DRD2 (0.50) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL18900330 | 0.76 | FLT3 (0.49) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL5973083 | 0.76 | KDM4E (0.58) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL2730199 | 0.76 | IDO1 (0.66) | KDM4EHPGDMAPTDAOSRD5A2 | |
| SCHEMBL30148093 | 0.76 | IDO1 (0.66) | KDM4EHPGDMAPTDAOSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |