SCHEMBL5161533

SCHEMBL5161533

CNCCNc1ccc(O)c2c1C(=O)c1c(O)cccc1C2=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.55
▸ KMT2A Q03164 6/20 0.55
▸ MAPK1 P28482 4/20 0.55
▸ TDP1 Q9NUW8 4/20 0.55
▸ LMNA P02545 3/20 0.55
▸ SMN1; SMN2 Q16637 3/20 0.55
▸ BLM P54132 3/20 0.55
▸ USP2 O75604 3/20 0.55
▸ RECQL P46063 3/20 0.55
▸ NSD2 O96028 3/20 0.55
▸ TP53 P04637 2/20 0.55
▸ ALOX15 P16050 2/20 0.55
▸ HTT P42858 2/20 0.55
▸ CSNK2A2 P19784 2/20 0.55
▸ CSNK2B P67870 2/20 0.55
▸ CSNK2A1 P68400 2/20 0.55
▸ CSNK2A3 Q8NEV1 2/20 0.55
▸ EGFR P00533 2/20 0.55
▸ NPC1 O15118 2/20 0.55
▸ MTOR P42345 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3288814 0.89 MEN1 (0.67) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL10962752 0.89 MEN1 (0.67) MEN1KMT2AMAPK1TDP1LMNA
Hydrochloric Acid SCHEMBL10524932 0.87 MEN1 (0.68) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL15691061 0.87 TERT (0.48) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL11041318 0.84 MEN1 (0.75) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL11275434 0.84 MEN1 (0.75) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL15957181 0.84 SMN1; SMN2 (0.52) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL6665858 0.84 CYP19A1 (0.78) MEN1KMT2AMAPK1TDP1LMNA
Hydrochloric Acid SCHEMBL11326845 0.84 TERT (0.48) MEN1KMT2AMAPK1TDP1LMNA
Hydrochloric Acid SCHEMBL10524280 0.83 BLM (0.76) MEN1KMT2AMAPK1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763673-B1 USES OF GEL FORMULATIONS BIOSTATUS LTD (GB) 2014-05-07 — — EP claimed
EP-1763673-A2 GEL FORMULATIONS AND USES THEREOF Biostatus Limited (GB) 2007-03-21 — — EP claimed
WO-2006003423-A2 GEL FORMULATIONS AND USES THEREOF BIOSTATUS LIMITED (GB) 2006-01-12 — — WO claimed
EP-1763673-B1 USES OF GEL FORMULATIONS BIOSTATUS LTD (GB) 2014-05-07 — — EP disclosed
EP-1763673-A2 GEL FORMULATIONS AND USES THEREOF Biostatus Limited (GB) 2007-03-21 — — EP disclosed
WO-2006003423-A2 GEL FORMULATIONS AND USES THEREOF BIOSTATUS LIMITED (GB) 2006-01-12 — — WO disclosed
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