Diphenylether

Diphenylether

SCHEMBL5161616

O=CCCC=O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.60
TSHR P16473 2/20 0.60
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
KMT2A Q03164 1/20 0.48
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
MAOA P21397 1/20 0.46
FFAR1 O14842 1/20 0.44
GSTP1 P09211 1/20 0.43
SOS1 Q07889 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
PARP10 Q53GL7 1/20 0.43
PLA2G2A P14555 1/20 0.43
SRD5A2 P31213 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL29240598 0.84 LTA4H (0.67) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL7185148 0.83 FFAR1 (0.58) LTA4HTSHRFFAR1SRD5A2
Diphenylether SCHEMBL27521610 0.83 LTA4H (0.57) LTA4HTSHRLMNAGAAKMT2A
Diphenylether SCHEMBL9796285 0.80 TSHR (0.57) LTA4HTSHR
SCHEMBL5324129 0.79 LTA4H (0.57) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL30341611 0.79 LTA4H (0.67) LTA4HTSHRLMNAGAAKMT2A
Diphenylether SCHEMBL29420763 0.79 LTA4H (0.67) LTA4HTSHRLMNAGAAKMT2A
Diphenylether SCHEMBL27568018 0.79 LTA4H (0.67) LTA4HTSHRLMNAGAAKMT2A
Diphenylether SCHEMBL27613970 0.79 LTA4H (0.67) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL7332622 0.79 FFAR1 (0.48) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1211094-B1 Thermal recording material FUJI PHOTO FILM CO LTD (JP) 2007-03-07 EP disclosed
US-6919297-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-07-19 US disclosed
US-20030118851-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-06-26 US disclosed