Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | LTA4H | P09960 | 4/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL28176491 | 0.84 | LTA4H (0.73) | TSHRLTA4HMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL11074700 | 0.84 | LTA4H (0.73) | TSHRLTA4HMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL11183529 | 0.84 | LTA4H (0.73) | TSHRLTA4HMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL11264556 | 0.84 | LTA4H (0.73) | TSHRLTA4HMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL9334093 | 0.82 | LTA4H (0.76) | TSHRLTA4HMMP2MMP3MMP9 | |
| Benzene SCHEMBL28034489 | 0.82 | TSHR (0.84) | TSHRFAAHTRPV1 | |
| Decanal SCHEMBL28179984 | 0.82 | TSHR (0.84) | TSHRFAAHTRPV1 | |
| Diphenylether SCHEMBL9420447 | 0.82 | TSHR (0.57) | TSHRLTA4HMMP2MMP3MMP9 | |
| Heptanal SCHEMBL28118481 | 0.81 | TSHR (0.61) | TSHRFAAHTRPV1 | |
| Diphenylether SCHEMBL5161616 | 0.80 | LTA4H (0.60) | TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053551-A | PROCESS FOR THE PRODUCTION OF ALDEHYDES BY HYDROFORMYLATION | DAVY MCKEE (LONDON) LIMITED (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0313559-A1 | PROCESS FOR THE PRODUCTION OF ALDEHYDES BY HYDROFORMYLATION. | DAVY MCKEE LONDON (GB) | 1989-05-03 | — | — | EP | disclosed |