SCHEMBL516165

SCHEMBL516165

CCOC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.62
P2RY2 P41231 2/20 0.48
P2RY4 P51582 2/20 0.48
P2RY6 Q15077 1/20 0.48
TYMS P04818 4/20 0.47
TK2 O00142 1/20 0.46
TK1 P04183 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1744123 1.00 DUT (0.62) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL10697851 0.91 DUT (0.60) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL2242406 0.89 DUT (0.63) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL17479412 0.88 DUT (0.62) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL12918449 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL26757491 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL438240 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL13153886 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL140597 0.87 DUT (0.66) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL6034461 0.87 DUT (0.66) DUTP2RY2P2RY4P2RY6TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9963696-B2 Method for screening mutant microorganism overproducing target metabolite using synthetic suicide genetic circuit KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2018-05-08 US claimed
US-20150376610-A1 METHOD FOR SCREENING MUTANT MICROORGANISM OVERPRODUCING TARGET METABOLITE USING SYNTHETIC SUICIDE GENETIC CIRCUIT KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2015-12-31 US claimed
EP-0642363-B1 USE OF HYDROGELS TO FIX BONE REPLACEMENTS M U R S T BR ITALIAN MINISTRY (IT) 2001-10-04 EP claimed
EP-0197718-B2 New medicaments for topical use FIDIA SPA (IT) 2001-07-25 EP claimed
EP-0792369-B1 SUICIDE GENES AND COMBINATIONS OF PYRIMIDINE NUCLEOSIDE AND NUCLEOBASE ANALOGUES WITH SUICIDE GENES FOR GENE THERAPY CAYLA (FR) 2000-04-05 EP claimed
US-5856153-A AN EUKARYOTIC VECTOR CONTAINING TWO EXPRESSION SUCIDE GENE UNITS, FIRST UNIT SENSITIZES TUMOR CELLS TO 5-FLUOROCYTOSINE AND SECOND EXPRESSION SUCIDE GENE UNIT SENSITIZES A MAMMAL CELL OR HIV-INFECTED CELLS TO AZIDOTHYMIDINE NUCLEOSIDE CAYLA (FR) 1999-01-05 US claimed
EP-0831794-A4 ACYCLOVIR DERIVATIVES FOR TOPICAL USE HOSTETLER KARL Y (US) 1998-11-04 EP claimed
EP-0831794-A1 ACYCLOVIR DERIVATIVES FOR TOPICAL USE HOSTETLER, Karl Y. (US) 1998-04-01 EP claimed
US-5645592-A COATED ON ORTHOPEDIC FASTENERS M.u.r.s.t. Italian Ministry for Universities and Scientific and Technological Research (IT) 1997-07-08 US claimed
WO-1996040088-A1 ACYCLOVIR DERIVATIVES FOR TOPICAL USE HOSTETLER KARL Y (US) 1996-12-19 WO claimed
US-5442053-A Salts and mixtures of hyaluronic acid with pharmaceutically active substances, pharmaceutical compositions containing the same and methods for administration of such compositions FIDIA, S.P.A. (IT) 1995-08-15 US claimed
EP-0642363-A1 USE OF HYDROGELS TO FIX BONE REPLACEMENTS M.U.R.S.T. ITALIAN MINISTRY FOR UNIVERSITY AND SCIENTIFIC AND TECHNOLOGICAL RESEARCH (IT) 1995-03-15 EP claimed
EP-0197718-B1 New medicaments for topical use FIDIA SPA (IT) 1993-12-15 EP claimed
WO-1993023094-A1 USE OF HYDROGELS TO FIX BONE REPLACEMENTS M.U.R.S.T., ITALIAN MINISTRY FOR UNIVERSITIES AND SCIENTIFIC AND TECHNOLOGICAL RESEARCH (IT) 1993-11-25 WO claimed
EP-0260428-A2 Cationic surfactants and pharmaceutical compositions containing them MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-23 EP claimed
CN-120118841-A Composition, induction method and application of chemical reprogramming induction functional ciRPE cells 瓯江实验室 2025-06-10 CN disclosed
CN-118871100-A Antiviral therapeutic agent and use thereof 西拉治疗公司 2024-10-29 CN disclosed
EP-0216453-A2 Esters of hyaluronic acid and their salts. FIDIA S.p.A. (IT) 1987-04-01 EP disclosed
EP-0197718-A2 New medicaments for topical use FIDIA S.p.A. (IT) 1986-10-15 EP disclosed
EP-0103783-A2 Dermatological preparation Dr. Thilo & Co. GmbH (DE) 1984-03-28 EP disclosed