SCHEMBL140597

SCHEMBL140597

O=c1ccn([C@@H]2CC(O)[C@H](COBr)O2)c(=O)[nH]1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.66
P2RY2 P41231 2/20 0.50
P2RY4 P51582 2/20 0.50
P2RY6 Q15077 1/20 0.50
TYMS P04818 4/20 0.49
SLC28A1 O00337 1/20 0.47
SLC28A2 O43868 1/20 0.47
SLC29A1 Q99808 1/20 0.47
SLC28A3 Q9HAS3 1/20 0.47
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TK1 P04183 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034461 0.90 DUT (0.66) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL15798318 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL2056624 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL4298071 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL13153886 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL3716323 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL438240 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL2009956 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL1255927 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL26757491 0.89 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8629262-B2 Detection of chromosomal inversions using non-repetitive nucleic acid probes COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2014-01-14 US claimed
US-6200257-B1 Catheter with permeable hydrogel membrane PROXIMA THERAPEUTICS, INC. 2001-03-13 US claimed
US-20260102450-A1 COMPOSITION AND FOOD SUPPLEMENTARY FOR SARCOPENIA AND PERIODONTAL DISEASES CONTAINING ALDER AND ELM COMPLEX EXTRACTS AS ACTIVE INGREDIENTS DR OREGONIN INC (KR) 2026-04-16 US disclosed
EP-3797770-B1 SOFTGEL CAPSULE COMPRISING APALUTAMIDE ARAGON PHARMACEUTICALS INC (US) 2026-02-18 EP disclosed
EP-2762558-B1 METHOD FOR PRODUCING TISSUE AND ORGAN PUBLIC UNIV CORP YOKOHAMA CITY UNIV (JP) 2026-01-21 EP disclosed
US-12496353-B2 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway SEAGEN INC. (US) 2025-12-16 US disclosed
US-20250319139-A1 METHODS FOR TREATING NEUROINFLAMMATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-10-16 US disclosed
US-20250270270-A1 COMPOSITION INCLUDING IL-32 THETA MUTANT AND USE THEREOF KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP (KR) 2025-08-28 US disclosed
WO-2025101652-A1 SELECTIVE MAMMALIAN STERILE 20-LIKE KINASE 1 (MST1) MODULATOR COMPOUNDS AS THERAPEUTICS FOR DIABETES AND LIVER REGENERATION THE SCRIPPS RESEARCH INSTITUTE (US) 2025-05-15 WO disclosed
US-20250134917-A1 COMPOSITIONS AND METHODS OF REGENERATING HEART TISSUES WITH AMINOGLYCOSIDES THE UAB RESEARCH FOUNDATION 2025-05-01 US disclosed
US-20250066864-A1 METHODS FOR IDENTIFYING ADAR1 INHIBITORS, AND COMPOSITIONS AND METHODS OF USE IN TREATING CANCER WISTAR INST (US) 2025-02-27 US disclosed
EP-0871475-A2 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 (IGF-BP3) IN TREATMENT OF P53-RELATED TUMORS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-10-21 EP disclosed
EP-0754187-A4 GROWTH ARREST HOMEOBOX GENE UNIV CASE WESTERN RESERVE (US) 1998-08-05 EP disclosed
WO-1997033989-A9 TRANSGENIC ANIMALS HAVING A DISRUPTED eNOS GENE AND USE THEREOF 1998-04-02 WO disclosed
WO-1997033989-A1 TRANSGENIC ANIMALS HAVING A DISRUPTED eNOS GENE AND USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 1997-09-18 WO disclosed
WO-1997026270-A2 SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES RIBOZYME PHARMACEUTICALS, INC. (US) 1997-07-24 WO disclosed
WO-1997009998-A2 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 (IGF-BP3) IN TREATMENT OF P53-RELATED TUMORS BRISTOL-MYERS SQUIBB COMPANY (US) 1997-03-20 WO disclosed
EP-0754187-A1 GROWTH ARREST HOMEOBOX GENE CASE WESTERN RESERVE UNIVERSITY (US) 1997-01-22 EP disclosed
WO-1995023161-A1 GROWTH ARREST HOMEOBOX GENE CASE WESTERN RESERVE UNIVERSITY (US) 1995-08-31 WO disclosed
WO-1990005789-A1 IN SITU SUPPRESSION HYBRIDIZATION AND USES THEREFOR YALE UNIVERSITY (US) 1990-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12496353-B2 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway MTOR, RICTOR, PIK3R5 DUT 2612/4885P2RY2 4536/4885P2RY4 4467/4885
US-20260102450-A1 COMPOSITION AND FOOD SUPPLEMENTARY FOR SARCOPENIA AND PERIODONTAL DISEASES CONTAINING ALDER AND ELM COMPLEX EXTRACTS AS ACTIVE INGREDIENTS MYOF, PYGM, MTPN DUT 3531/4885P2RY2 1241/4885P2RY4 1432/4885
US-20250066864-A1 METHODS FOR IDENTIFYING ADAR1 INHIBITORS, AND COMPOSITIONS AND METHODS OF USE IN TREATING CANCER ADA, ADAR, NTPCR DUT 36/4885P2RY2 823/4885P2RY4 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.