SCHEMBL5161970

SCHEMBL5161970

CC(C)(C)OC(=O)COc1cccc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
KDM4E B2RXH2 6/20 0.62
HPGD P15428 4/20 0.62
TDP1 Q9NUW8 1/20 0.62
TSHR P16473 1/20 0.57
OGG1 O15527 1/20 0.56
HSD17B10 Q99714 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HTT P42858 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2C9 P11712 1/20 0.48
MAPT P10636 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
DAPK1 P53355 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5697619 0.91 DDB1 (0.49) ALDH1A1KDM4EHPGDTDP1TSHR
SCHEMBL28591165 0.87 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1TSHR
Diphenylsulfane SCHEMBL27967515 0.87 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDTDP1TSHR
SCHEMBL22656552 0.85 POLB (0.50) ALDH1A1KDM4EHPGDTSHRHSD17B10
SCHEMBL22610037 0.85 LMNA (0.47) ALDH1A1KDM4EHPGDTDP1TSHR
SCHEMBL2758525 0.85 HPGD (0.46) ALDH1A1KDM4EHPGDTDP1TSHR
SCHEMBL7277563 0.84 CNR2 (0.54) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL2758527 0.84 DDB1 (0.45) ALDH1A1KDM4EHPGDTDP1TSHR
SCHEMBL1368627 0.83 RXFP1 (0.64) ALDH1A1HPGDTSHRL3MBTL1KMT2A
Diphenylsulfane SCHEMBL28669697 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757980-A1 Radiation sensitive resin composition JSR Corporation (JP) 2007-02-28 EP disclosed
EP-1757980-A1 Radiation sensitive resin composition JSR Corporation (JP) 2007-02-28 EP disclosed
US-20070042292-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-02-22 US disclosed
US-20070042292-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-02-22 US disclosed
US-20070042292-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-02-22 US disclosed
EP-1441256-B1 Radiation-sensitive resin composition JSR CORP (JP) 2006-05-31 EP disclosed
EP-0789278-B1 Radiation-sensitive resin composition JSR CORP (JP) 2005-05-04 EP disclosed
EP-1441256-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2004-07-28 EP disclosed
US-6727032-B1 USEFUL IN MICRO-PROCESSING USING VARIOUS RADIATIONS, E.G., FAR-ULTRAVIOLET RADIATION SUCH AS KRF EXCIMER LASER OR ARF EXCIMER LASER, X RAYS SUCH AS SYNCHROTRON RADIATION, CHARGED PARTICLE RADIATION SUCH AS ELECTRON BEAM, ETC. JSR CORPORATION (JP) 2004-04-27 US disclosed
US-6692887-B1 COPOLYMER OF SUCH AS MALEIC ANHYDRIDE AND NORBORNENE ACID CLEAVABLE DERIVATIVE; TRANSPARENCY; DRY ETCHING RESISTANCE; PHOTORESIST PATTERN WITH HIGH ADHESION, SENSITIVITY, RESOLUTION AND DEVELOPABILITY JSR CORPORATION (JP) 2004-02-17 US disclosed
US-6111143-A BY ONE-STEP REACTION BETWEEN SULFOXIDE COMPOUND AND AROMATIC COMPOUND IN PRESENCE OF PERFLUOROALKANESULFONIC ANHYDRIDE; USE AS POLYMERIZATION PHOTOINITIATOR, OR PHOTOACID GENERATOR LEAVING THE PROTECTION GROUPS OF ORGANIC COMPOUNDS KOREA KUMBO PETROCHEMICAL CO., LTD. (KR) 2000-08-29 US disclosed
EP-0972761-A1 Sulfonium salt and its manufacturing method Korea Kumho Petrochemical Co. Ltd. (KR) 2000-01-19 EP disclosed
EP-0789278-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-08-13 EP disclosed