Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Triethyl Citrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethyl Citrate SCHEMBL901127 | 0.94 | GAA (0.48) | PKMGAAKDM4EMGAMSI | |
| Triethyl Citrate SCHEMBL23465 | 0.94 | GAA (0.48) | PKMGAAKDM4EMGAMSI | |
| Triethyl Citrate SCHEMBL28041956 | 0.92 | GAA (0.46) | PKMGAAKDM4EMGAMSI | |
| Triethyl Citrate SCHEMBL29035980 | 0.92 | GAA (0.46) | PKMGAAKDM4EMGAMSI | |
| Triethyl Citrate SCHEMBL6236671 | 0.92 | GAA (0.46) | PKMGAAKDM4EMGAMSI | |
| Triethyl Citrate SCHEMBL14856311 | 0.92 | GAA (0.46) | PKMGAAKDM4EMGAMSI | |
| SCHEMBL73473 | 0.90 | ALDH1A1 (0.41) | PKMGAAKDM4EMGAMSI | |
| SCHEMBL15695762 | 0.90 | PKM (0.42) | PKMGAAKDM4EMGAMSI | |
| Triethyl Citrate SCHEMBL30812452 | 0.90 | ALDH1A1 (0.41) | PKMGAAKDM4EMGAMSI | |
| Triethyl Citrate SCHEMBL17898236 | 0.90 | GAA (0.44) | PKMGAAKDM4EMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270137-A1 | COATED COMPOSITIONS OF BIOLOGICALLY ACTIVE INGREDIENTS FOR ORAL ADMINISTRATION TO RUMINANTS | EVONIK OPERATIONS GMBH (DE) | 2023-08-31 | — | — | US | claimed |
| CN-105102615-A | Phytase formulations | BASF ENZYMES LLC | 2015-11-25 | — | — | CN | claimed |
| CN-103080264-B | Detergent aqueous emulsion pressure sensitive adhesive and method for preparing the same | LG CHEM, LTD. (KR) | 2015-08-12 | — | — | CN | claimed |
| CN-103897311-A | Environmental protection type plasticizer | JIAOZHOU FUTIAN CHEMICAL CO LTD | 2014-07-02 | — | — | CN | claimed |
| CN-102108194-B | Polylactic acid/fatty dibasic acid and diol polyester composite | TORAY FIBER RES INST CN CO LTD | 2013-06-26 | — | — | CN | claimed |
| CN-103131052-A | Biodegradable plastic material based on cellulose acetate and relative end-products | ES LAMINATI ESTRUSI TERMOPLASTICI S P A | 2013-06-05 | — | — | CN | claimed |
| CN-103080264-A | Detergent aqueous emulsion pressure sensitive adhesive and method for preparing the same | LG CHEMICAL LTD | 2013-05-01 | — | — | CN | claimed |
| CN-103011228-A | Preparation method of ultrafine coating light calcium carbonate | SHANDONG DONGSHENG NEW MAT CO | 2013-04-03 | — | — | CN | claimed |
| CN-102731976-A | Polyester composition and its prepared film | TORAY FIBER RES INST CN CO LTD | 2012-10-17 | — | — | CN | claimed |
| CN-102108194-A | Polylactic acid/fatty dibasic acid and diol polyester composite | TORAY FIBER RES INST CN CO LTD | 2011-06-29 | — | — | CN | claimed |
| CN-101668854-A | Compositions, systems, and methods for preserving and/or stabilizing cells and/or macromolecules | SIERRA MOLECULAR CORP | 2010-03-10 | — | — | CN | claimed |
| CN-101437908-A | Hydrophilic fouling release coatings and uses thereof | EASTMAN CHEM CO (US) | 2009-05-20 | — | — | CN | claimed |
| CN-100422299-C | Detergent compsns. comprising hydrotropes | P & G CO (US) | 2008-10-01 | — | — | CN | claimed |
| CN-101240074-A | Degradable granule and its related method | HALLIBURTON ENERGY SERV INC (US) | 2008-08-13 | — | — | CN | claimed |
| CN-101098944-A | Abrasive composition | 3M INNOVATIVE PROPERTIES CO (US) | 2008-01-02 | — | — | CN | claimed |
| CN-1227188-C | Apparatus for igniting gas generating material | CRITICAL SAFETY SYSTEM INC (US) | 2005-11-16 | — | — | CN | claimed |
| CN-1535256-A | Autoignition material for gas generator | �����ɷ� | 2004-10-06 | — | — | CN | claimed |
| CN-1478062-A | Apparatus for igniting gas generating material | �����ɷ� | 2004-02-25 | — | — | CN | claimed |
| CN-108289848-A | Pharmaceutical compositions comprising potent inhibitors of URAT1 | 阿迪亚生命科学公司 | 2018-07-17 | — | — | CN | disclosed |
| EP-0299205-A1 | Sustained release microcapsules and method for the production thereof | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM HIGHER EDUCATION (US) | 1989-01-18 | — | — | EP | disclosed |