Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28140378 | 0.86 | ALDH1A1 (0.54) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL20691434 | 0.84 | MAPT (0.53) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL27367228 | 0.84 | TDP1 (0.45) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL10458171 | 0.83 | TDP1 (0.70) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL14477213 | 0.82 | TDP1 (0.63) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL16173560 | 0.82 | TDP1 (0.63) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL51601 | 0.81 | TDP1 (0.68) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL28875175 | 0.81 | TDP1 (0.68) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL137486 | 0.81 | TDP1 (0.83) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL17459902 | 0.79 | TDP1 (0.78) | TDP1MAPK1HIF1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109346-A | High-hardness self-lubricating EPDM shaft pin sleeve material and preparation method thereof | 安徽亚新科密封技术有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-112851501-A | Chemical tracer for fracturing and preparation method and application thereof | 中国石油大学(华东) | 2021-05-28 | — | — | CN | claimed |
| CN-106459744-B | Double-core main group metal phosphorescent emitters | 西门子公司 | 2019-08-30 | — | — | CN | claimed |
| CN-107488146-A | ICD derivative and its preparation method and application | 中国科学院兰州化学物理研究所 | 2017-12-19 | — | — | CN | claimed |
| CN-104558284-B | Catalytic component for olefinic polymerization and preparation method thereof and the catalyst for olefinic polymerization and application | 中国石油化工股份有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-106459744-A | Bi-nuclear main group metal phosphorescent emitter | 西门子公司 | 2017-02-22 | — | — | CN | claimed |
| CN-104558284-A | Catalyst component used for olefin polymerization and preparation method thereof as well as catalyst used for olefin polymerization and application | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | claimed |
| CN-103145693-B | Preparation method of imatinib | CHENGDU BAIYU SCIENCE & TECHNOLOGY PHARMACEUTICAL CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-103402996-B | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (AMD) | NOVARTIS AG | 2015-02-11 | — | — | CN | claimed |
| CN-102753522-B | Substituted pyrrolidine-2-carboxamides | HOFFMANN LA ROCHE | 2013-11-27 | — | — | CN | claimed |
| CN-103145693-A | Preparation method of imatinib | CHENGDU BAIYU TECHNOLOGY PHARMACEUTICAL CO LTD | 2013-06-12 | — | — | CN | claimed |
| CN-101089020-B | VIP analog and its radioactive marker and their preparation process | SHANGHAI INST APPLIED PHYSICS | 2011-04-20 | — | — | CN | claimed |
| CN-101089020-A | VIP analog and its radioactive marker and their prepn process | SHANGHAI INST APPLIED PHYSICS (CN) | 2007-12-19 | — | — | CN | claimed |
| CN-119569655-A | Pyrazolecarboxamide-containing fluorine methyl thioester benzoate compound and preparation method and application thereof | 西北大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-115109346-B | High-hardness self-lubricating EPDM shaft pin sleeve material and preparation method thereof | 安徽亚新科密封技术有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2023165591-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) | 2023-09-07 | — | — | WO | disclosed |
| US-6187284-B1 | REACTING A PEPTIDE COMPRISING A FREE THIOL GROUP WITH AN 18 F-BOUND LABELLING REAGENT WHICH ALSO HAS A GROUP THAT IS REACTIVE WITH THIOLS. | IMMUNOMEDICS, INC. | 2001-02-13 | — | — | US | disclosed |
| EP-1009726-A1 | FLUORINATION OF PROTEINS AND PEPTIDES FOR F-18 POSITRON EMISSION TOMOGRAPHY | Immunomedics, Inc. (US) | 2000-06-21 | — | — | EP | disclosed |
| CN-1227545-A | 3-cyanoaryl pyrazoles and use thereof as herbicides | BAYER AG (DE) | 1999-09-01 | — | — | CN | disclosed |
| WO-1999011590-A1 | FLUORINATION OF PROTEINS AND PEPTIDES FOR F-18 POSITRON EMISSION TOMOGRAPHY | IMMUNOMEDICS, INC. (US) | 1999-03-11 | — | — | WO | disclosed |