SCHEMBL51601

SCHEMBL51601

O=C(OCOC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.68
MAPK1 P28482 1/20 0.65
HIF1A Q16665 1/20 0.65
SLC6A2 P23975 1/20 0.65
SLC6A3 Q01959 1/20 0.65
KMT2A Q03164 1/20 0.65
LMNA P02545 3/20 0.63
ALDH1A1 P00352 2/20 0.63
F2 P00734 1/20 0.61
TSHR P16473 3/20 0.59
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 2/20 0.55
GAA P10253 2/20 0.55
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
HPGD P15428 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
PPARG P37231 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28875175 1.00 TDP1 (0.68) TDP1MAPK1HIF1ASLC6A2SLC6A3
Ethylene Glycol SCHEMBL15661698 0.93 ALDH1A1 (0.62) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL9817384 0.91 TDP1 (0.59) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL4570317 0.91 TDP1 (0.59) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL21953404 0.91 TDP1 (0.67) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL7935103 0.89 TDP1 (0.57) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL2652364 0.89 LMNA (0.58) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL5157212 0.89 LMNA (0.70) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL5210552 0.89 TDP1 (0.57) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL7371028 0.89 TDP1 (0.57) TDP1MAPK1HIF1ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117070156-A Ultraviolet-resistant aging-resistant PVC adhesive tape and preparation system thereof 福建友谊胶粘带集团有限公司 2023-11-17 CN claimed
CN-116003447-A Hg used in aqueous solution 2+ Fluorescent probe for ion detection 沈阳化工大学 2023-04-25 CN claimed
CN-110573535-B Electron donors for ziegler-natta precatalyst preparation and catalyst systems for olefin polymerization 格雷斯公司 2022-07-08 CN claimed
CN-107207700-B Method for synthesizing polyoxazolidone compound with high stability 科思创德国股份有限公司 2021-04-27 CN claimed
CN-110573535-A Electron donors for ziegler-natta precatalyst preparation and catalyst systems for olefin polymerization 格雷斯公司 2019-12-13 CN claimed
US-10385167-B2 Process for the synthesis of polyoxazolidinone compounds with high stability COVESTRO DEUTSCHLAND AG (DE) 2019-08-20 US claimed
EP-3256508-B1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY COVESTRO DEUTSCHLAND AG (DE) 2019-03-27 EP claimed
US-20180022871-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY COVESTRO DEUTSCHLAND AG (DE) 2018-01-25 US claimed
EP-3256508-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY Covestro Deutschland AG (DE) 2017-12-20 EP claimed
WO-2016128380-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY COVESTRO DEUTSCHLAND AG (DE) 2016-08-18 WO claimed
EP-0489536-A2 Olefin polymerisation catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-10 EP claimed
EP-0263492-B1 RETINOIDS, THEIR PREPARATION AND USE AS PHARMACEUTICAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 1991-03-13 EP claimed
US-4900478-A SKIN DISORDERS HOFFMANN-LA ROCHE INC. (US) 1990-02-13 US claimed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
WO-2026087975-A1 THERMOSENSITIVE RECORDING MEDIUM AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2026-04-30 WO disclosed
EP-4733080-A1 HEAT-SENSITIVE RECORDING BODY AND METHOD FOR PRODUCING SAME Nippon Paper Industries Co., Ltd. (JP) 2026-04-29 EP disclosed
US-4313956-A Novel sypathomimetic amine prodrugs INTERX RESEARCH CORP. (US) 1982-02-02 US disclosed
US-4311706-A ADRENERGIC STIMULANTS INTERX RESEARCH CORPORATION (US) 1982-01-19 US disclosed
US-4026798-A PROLONGING USE FMC CORPORATION (US) 1977-05-31 US disclosed
US-4013575-A Dry cleaning with peracids FMC CORPORATION (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA TDP1 2624/4885MAPK1 308/4885HIF1A 1935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.