Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329840 | 0.78 | CA4 (0.39) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL7629299 | 0.69 | APP (0.35) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL4825183 | 0.67 | — | — | |
| SCHEMBL8668815 | 0.67 | — | — | |
| SCHEMBL38901 | 0.63 | ALDH1A1 (0.40) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL1778033 | 0.63 | ALDH1A1 (0.40) | ALDH1A1CA12CA1CA2GLA | |
| Naphthalene SCHEMBL10438031 | 0.61 | CYP2A6 (0.80) | ALDH1A1ALOX15CA12CA1CA2 | |
| Naphthalene SCHEMBL11145450 | 0.61 | CYP2A6 (0.80) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL28331870 | 0.61 | CA4 (0.36) | ALDH1A1ALOX15CA12CA1CA2 | |
| Fluoride SCHEMBL28572273 | 0.60 | ALDH1A1 (0.38) | ALDH1A1ALOX15CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1234829-B1 | SILICON-CONTAINING POLYMERS | NAT INST OF ADVANCED IND SCIEN (JP) | 2007-03-07 | — | — | EP | disclosed |
| US-6753401-B1 | DEHYDROGENATIVE POLYMERIZATION OF QUINONE AND/OR DIOL WITH TRIHYDROSILANE OR DIHYDROSILANE IN PRESENCE OF PALLADIUM-CONTAINING CATALYST; POLYSILANES | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2004-06-22 | — | — | US | disclosed |
| EP-1234829-A1 | SILICON-CONTAINING POLYMERS | National Institute of Advanced Industrial Science and Technology (JP) | 2002-08-28 | — | — | EP | disclosed |