Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292238 | 0.69 | ALDH1A1 (0.37) | ALDH1A1TSHRCES2CES1DAO | |
| SCHEMBL10038833 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHRCES2CES1DAO | |
| SCHEMBL9329840 | 0.69 | CA4 (0.39) | APPALDH1A1TSHRCES2CES1 | |
| SCHEMBL5162225 | 0.69 | ALDH1A1 (0.35) | APPALDH1A1ALOX15CYP2A6CA1 | |
| SCHEMBL1778033 | 0.67 | ALDH1A1 (0.40) | APPALDH1A1TSHRCYP2A6LMNA | |
| Benzene SCHEMBL28223369 | 0.67 | ALDH1A1 (0.40) | APPALDH1A1TSHRALOX15CYP2A6 | |
| SCHEMBL38901 | 0.67 | ALDH1A1 (0.40) | APPALDH1A1TSHRALOX15CYP2A6 | |
| Benzene SCHEMBL27879268 | 0.67 | ALDH1A1 (0.40) | APPALDH1A1TSHRALOX15CYP2A6 | |
| SCHEMBL27481434 | 0.67 | CA1 (0.37) | ALDH1A1TSHRCES2CES1DAO | |
| SCHEMBL7764353 | 0.65 | TDP1 (0.35) | ALDH1A1TSHRCES2CES1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455458-B1 | HIGH MOLECULAR WEIGHT POLYOLEFIN; GROUP 4 TRANSITION METAL COMPLEXES HAVING A BIDENTATE ANCILLARY LIGAND SYSTEM OF ONE CYCLOPENTADIENYL GROUP BOUND TO THE TRANSITION METAL AND A GROUP 15 OR GROUP 16 ATOM COVALENTLY BOUND THROUGH A BRIDGING | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-09-24 | — | — | US | disclosed |
| EP-1097161-A1 | TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002891-A1 | TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2000-01-20 | — | — | WO | disclosed |