SCHEMBL5162230

SCHEMBL5162230

CCOC(=O)C(CC)N1C(=O)C=CC1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.49
GSK3B P49841 1/20 0.49
ALDH1A1 P00352 5/20 0.42
HPGD P15428 3/20 0.42
NPSR1 Q6W5P4 3/20 0.42
HTT P42858 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
HSP90AA1 P07900 1/20 0.42
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42
MAPT P10636 3/20 0.42
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
PKM P14618 1/20 0.42
CCR6 P51684 1/20 0.42
BLM P54132 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
WRN Q14191 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5164277 0.86 ALDH1A1 (0.40) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL5161621 0.85 ALDH1A1 (0.42) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL21122458 0.84 GSK3A (0.45) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL15024127 0.84 ALDH1A1 (0.39) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL5165284 0.83 GSK3A (0.44) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL15023913 0.83 ALDH1A1 (0.38) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL5160676 0.83 TSHR (0.40) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL15024001 0.82 ALDH1A1 (0.40) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL21122455 0.82 GSK3A (0.50) GSK3AGSK3BALDH1A1HPGDNPSR1
SCHEMBL5166265 0.82 MAPK1 (0.43) ALDH1A1NPSR1MAPTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1582548-B1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK & CHEMICALS (JP) 2007-03-28 EP disclosed
US-7141642-B2 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-11-28 US disclosed
US-20060047140-A1 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-03-02 US disclosed
EP-1582548-A1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047140-A1 Process for producing polymerizable polybranched polyester ACSL4, ACSL1, HACL2 GSK3A 2879/4885GSK3B 3375/4885ALDH1A1 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.