Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452387 | 1.00 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL3451910 | 0.99 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL3451912 | 0.99 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL13109489 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL3452144 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL13109486 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL3451704 | 0.89 | GSTO1 (0.42) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL3451702 | 0.89 | GSTO1 (0.42) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL13109500 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL3452312 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753735-A1 | SUBSTITUTED THIAZOLE AND PYRIMIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | Transtech Pharma, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-11-24 | — | — | US | claimed |
| WO-2005103022-A1 | SUBSTITUTED THIAZOLE AND PYRIMIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | TRANSTECH PHARMA, INC. (US) | 2005-11-03 | — | — | WO | claimed |
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | MC5R, MC3R, MC4R | ITGB3 1281/4885ITGA2B 1854/4885ALDH1A1 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.