Itaconate

Itaconate

SCHEMBL5162676

C=C(CC(=O)O)C(=O)O.C=CC=CC(C)C(=C)C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709405 0.86
Maleic Acid SCHEMBL9402863 0.79 GABRP (0.38) ALOX15HSD17B10
Itaconate SCHEMBL4294336 0.75 ALOX15 (0.77) ALOX15HSD17B10
Itaconate SCHEMBL28350321 0.73 ALOX15 (0.60) ALOX15HSD17B10
Itaconate SCHEMBL27498028 0.73 ALOX15 (0.74) ALOX15HSD17B10
Itaconate SCHEMBL27146278 0.73 ALOX15 (0.71) ALOX15HSD17B10
Itaconate SCHEMBL18554417 0.73 ALOX15 (0.71) ALOX15HSD17B10
Itaconate SCHEMBL28198866 0.72 ALOX15 (0.71) ALOX15HSD17B10
Itaconate SCHEMBL3625755 0.71 ALOX15 (0.77) ALOX15HSD17B10
Itaconate SCHEMBL5447650 0.71 ALOX15 (0.68) ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1306719-B1 Silver halide photographic material showing improved latent image stability AGFA GEVAERT (BE) 2007-03-07 EP claimed
US-20030157446-A1 Silver halide photographic material showing improved latent image stability AGFA-GEVAERT (BE) 2003-08-21 US claimed
EP-1306719-A1 Silver halide photographic material showing improved latent image stability Agfa-Gevaert (BE) 2003-05-02 EP claimed
EP-0831362-A1 Silver halide light-sensitive material with colloidal silica as protective colloid coated from layers without or with minimum amounts of gelatin as a binder material AGFA-GEVAERT N.V. (BE) 1998-03-25 EP claimed
EP-1306719-B1 Silver halide photographic material showing improved latent image stability AGFA GEVAERT (BE) 2007-03-07 EP disclosed
US-20030157446-A1 Silver halide photographic material showing improved latent image stability AGFA-GEVAERT (BE) 2003-08-21 US disclosed
EP-1306719-A1 Silver halide photographic material showing improved latent image stability Agfa-Gevaert (BE) 2003-05-02 EP disclosed
EP-0831362-A1 Silver halide light-sensitive material with colloidal silica as protective colloid coated from layers without or with minimum amounts of gelatin as a binder material AGFA-GEVAERT N.V. (BE) 1998-03-25 EP disclosed
WO-1996010214-A1 NEGATIVE WORKING OVERLAY COLOUR PROOFING SYSTEM AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1996-04-04 WO disclosed
WO-1994010610-A1 PROCESS FOR FORMING DIRECT DIGITAL COLOUR PROOFS ON PRINT STOCK MATERIAL AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1994-05-11 WO disclosed