SCHEMBL516275

SCHEMBL516275

O=c1cc(-c2ccccc2)c2ccccc2o1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 5/20 0.68
CA12 O43570 4/20 0.68
AKR1B1 P15121 2/20 0.68
MAOB P27338 2/20 0.68
ALDH2 P05091 1/20 0.68
MAOA P21397 1/20 0.68
HSD17B3 P37058 1/20 0.68
SORD Q00796 1/20 0.68
MCL1 Q07820 1/20 0.65
NQO1 P15559 1/20 0.58
CYP1B1 Q16678 2/20 0.56
CYP1A1 P04798 1/20 0.56
CYP1A2 P05177 1/20 0.56
CA1 P00915 2/20 0.56
HPGD P15428 5/20 0.55
ALDH1A1 P00352 5/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
GABRP O00591 1/20 0.53
GABRD O14764 1/20 0.53
NPC1 O15118 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31264770 1.00 CA9 (0.68) CA9CA12AKR1B1MAOBALDH2
SCHEMBL29182638 0.96 CA9 (0.64) CA9CA12AKR1B1MAOBALDH2
SCHEMBL5396825 0.88 NQO1 (0.67) CA9CA12AKR1B1MAOBALDH2
SCHEMBL29182639 0.87 CA9 (0.54) CA9CA12AKR1B1MAOBALDH2
SCHEMBL9845372 0.86 GABRP (0.58) CA9CA12AKR1B1MAOBALDH2
SCHEMBL1181618 0.86 CA12 (0.69) CA9CA12AKR1B1MAOBALDH2
SCHEMBL20420777 0.84 CA9 (0.54) CA9CA12AKR1B1MAOBALDH2
SCHEMBL13769543 0.83 CA12 (0.70) CA9CA12AKR1B1MAOBALDH2
SCHEMBL28053824 0.83 GABRP (0.60) CA9CA12AKR1B1MAOBALDH2
SCHEMBL28186315 0.83 CA9 (0.54) CA9CA12AKR1B1MAOBALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694880-A1 POLYPHENOL-CONTAINING COMPOSITIONS FOR UPREGULATING GENE EXPRESSION The Board of Trustees of the Leland Stanford Junior University (US) 2026-02-18 EP claimed
CN-119841797-A 3-Arylation/3-alkenylation coumarin compound, preparation method and application thereof 云南民族大学 2025-04-18 CN claimed
CN-119587702-A Pharmaceutical composition capable of improving bioavailability of oral statin drugs and application thereof 强生化学制药厂股份有限公司 2025-03-11 CN claimed
WO-2024216192-A1 POLYPHENOL-CONTAINING COMPOSITIONS FOR UPREGULATING CAMP GENE EXPRESSION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-10-17 WO claimed
CN-113453658-B Method for dyeing or making up eyebrows LVMH研究公司 2024-05-03 CN claimed
EP-3636600-B1 A SORPTION COMPOSITION FOR COMPLEX WATER PURIFICATION EWI BVBA (BE) 2022-11-30 EP claimed
EP-3636600-A1 A SORPTION COMPOSITION FOR COMPLEX WATER PURIFICATION EWI bvba (BE) 2020-04-15 EP claimed
CN-105085460-B A kind of preparation method of 4 phenyl coumarin class compound 浙江工业大学 2017-07-28 CN claimed
US-9127092-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-09-08 US claimed
US-20140187725-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
US-20100199370-A1 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research 2010-08-05 US claimed
EP-2131646-A2 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organisation, Volcani Center (IL) 2009-12-16 EP claimed
WO-2008096354-A2 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O.), THE VOLCANL CENTER (IL) 2008-08-14 WO claimed
EP-4223293-B1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF PROSTATE CANCER TOKYO METROPOLITAN GERIATRIC HOSPITAL AND INST OF GERONTOLOGY (JP) 2026-05-27 EP disclosed
EP-4724064-A1 COMPOSITION COMPRISING A COMBINATION OF A CORTICOSTEROID AND A FLAVONOID FOR USE IN TREATING EYE-RELATED DISEASES South East Technological University (IE) 2026-04-15 EP disclosed
US-20260097130-A1 METHOD FOR TREATING NEURODEGENERATIVE DISEASES SUNTEC MEDICAL INC (US) 2026-04-09 US disclosed
US-6420571-B2 Methods for preparing antiviral calanolide compounds SARAWAK MEDICHEM PHARMACEUTICALS, INC. 2002-07-16 US disclosed
US-6369241-B1 MULTISTAGE REACTION OF KETOESTER WITH 1,3,5-TRIHYDROXYBENZENE TO PRODUCE DIHYDROXYOXOCOUMARONE, COUPLING AND CYCLIZATION SARAWAK MEDICHEM PHARMACEUTICALS, INC. 2002-04-09 US disclosed
US-20020013480-A1 Methods for preparing antiviral calanolide compounds SARAWAK MEDICHEM PHARMACEUTICALS, INC. 2002-01-31 US disclosed
WO-1998025608-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A 4-ARYLCOUMARIN FOR THE TREATMENT OF VIRAL INFECTIONS BIO'S S.R.L. (IT) 1998-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013480-A1 Methods for preparing antiviral calanolide compounds ZC3HAV1, ZC3HAV1L, CYP8B1 CA9 1469/4885CA12 868/4885AKR1B1 569/4885
US-20260097130-A1 METHOD FOR TREATING NEURODEGENERATIVE DISEASES CD44, L1CAM, CD14 CA9 3659/4885CA12 2714/4885AKR1B1 4276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.